Body Weight Control by a High-Carbohydrate/Low-Fat Diet Slows the Progression of Diabetic Kidney Damage in an Obese, Hypertensive, Type 2 Diabetic Rat Model

Body Weight Control by a High-Carbohydrate/Low-Fat Diet Slows the Progression of Diabetic Kidney Damage in an Obese, Hypertensive, Type 2 Diabetic Rat Model

Obesity is one of several factors implicated in the genesis of diabetic nephropathy (DN). Obese, hypertensive, type 2 diabetic rats SHR/NDmcr-cp were given, for 12 weeks, either a normal, middle-carbohydrate/middle-fat diet (MC/MF group) or a high-carbohydrate/low-fat diet (HC/LF group). Daily calor...

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Main Authors: Shuichi Ohtomo, Yuko Izuhara, Masaomi Nangaku, Takashi Dan, Sadayoshi Ito, Charles van Ypersele de Strihou, Toshio Miyata
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2010/136502
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