Pitfalls in Labelled Leukocyte Scanning
Radiolabelled leukocyte scanning is a valuable tool in the diagnosis and management of inflammatory bowel disease (IBO). As well as determining the presence or absence of disease and its complications, the degree of inflammation may be quantified either visually or numerically following four day fec...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1990-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1990/317681 |
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| Summary: | Radiolabelled leukocyte scanning is a valuable tool in the diagnosis
and management of inflammatory bowel disease (IBO). As well as determining
the presence or absence of disease and its complications, the degree of
inflammation may be quantified either visually or numerically following four day
fecal collection. The authors discuss the labelling techniques currently in use and
the appearance of IBO using both 111Indium and 99mTechnetium as the labelling
isotope. The advantages and disadvantages of each technique are compared.
Certain diagnostic pitfalls and causes of false-positive results including radiation
enteritis, nonsteroidal anti-inflammatory drug ingestion and intra- and extra-abdominal
sepsis are discussed in full, and it is shown that in most cases good
labelling technique, careful imaging and awareness of alternative mechanisms
for leukocyte appearance in the gastrointestinal tract will ensure correct interpretation
of these scans. |
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| ISSN: | 0835-7900 |