Reactive arthritis incidence in a community cohort following a large waterborne campylobacteriosis outbreak in Havelock North, New Zealand
Objectives In August 2016, Campylobacter spp contaminated an untreated reticulated water supply resulting in a large-scale gastroenteritis outbreak affecting an estimated 8320 people. We aimed to determine the incidence of probable reactive arthritis (ReA) cases in individuals with culture-confirmed...
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BMJ Publishing Group
2022-06-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/6/e060173.full |
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| author | Nicholas Jones Rebecca Grainger Michael G Baker Tim Wood Tiffany A Walker Terence Quirke Rebekah Roos Jill Sherwood Graham Mackereth Tomasz Kiedrzynski Rachel Eyre Shevaun Paine Anita Jagroop |
| author_facet | Nicholas Jones Rebecca Grainger Michael G Baker Tim Wood Tiffany A Walker Terence Quirke Rebekah Roos Jill Sherwood Graham Mackereth Tomasz Kiedrzynski Rachel Eyre Shevaun Paine Anita Jagroop |
| author_sort | Nicholas Jones |
| collection | DOAJ |
| description | Objectives In August 2016, Campylobacter spp contaminated an untreated reticulated water supply resulting in a large-scale gastroenteritis outbreak affecting an estimated 8320 people. We aimed to determine the incidence of probable reactive arthritis (ReA) cases in individuals with culture-confirmed campylobacteriosis (CC), self-reported probable campylobacteriosis (PC) and those reporting no diarrhoea (ND).Design We conducted a retrospective cohort study to identify incidence of probable ReA cases. We identified cases with new ReA symptoms using an adapted acute ReA (AReA) telephone questionnaire. Those reporting ≥1 symptom underwent a telephone interview with the study rheumatologist. Probable ReA was defined as spontaneous onset of pain suggestive of inflammatory arthritis in ≥1 previously asymptomatic joint for ≥3 days occurring ≤12 weeks after outbreak onset.Setting Population-based epidemiological study in Havelock North, New Zealand.Participants We enrolled notified CC cases with gastroenteritis symptom onsets 5 August 2016–6 September 2016 and conducted a telephone survey of households supplied by the contaminated water source to enrol PC and ND cases.Results One hundred and six (47.3%) CC, 47 (32.6%) PC and 113 (34.3%) ND cases completed the AReA telephone questionnaire. Of those reporting ≥1 new ReA symptom, 45 (75.0%) CC, 13 (68.4%) PC and 14 (82.4%) ND cases completed the rheumatologist telephone interview. Nineteen CC, 4 PC and 2 ND cases developed probable ReA, resulting in minimum incidences of 8.5%, 2.8% and 0.6% and maximum incidences of 23.9%, 12.4% and 2.15%.Discussion We describe high probable ReA incidences among gastroenteritis case types during a very large Campylobacter gastroenteritis outbreak using a resource-efficient method that is feasible to employ in future outbreaks. |
| format | Article |
| id | doaj-art-4231ed01ec934237be8cb213b5642ebd |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-4231ed01ec934237be8cb213b5642ebd2025-01-28T07:55:09ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2021-060173Reactive arthritis incidence in a community cohort following a large waterborne campylobacteriosis outbreak in Havelock North, New ZealandNicholas Jones0Rebecca Grainger1Michael G Baker2Tim Wood3Tiffany A Walker4Terence Quirke5Rebekah Roos6Jill Sherwood7Graham Mackereth8Tomasz Kiedrzynski9Rachel Eyre10Shevaun Paine11Anita Jagroop12Hawke`s Bay District Health Board, Napier, The New Zealand4 Department of Medicine, University of Otago, Wellington, New ZealandDepartment of Public Health, University of Otago, Dunedin, The New ZealandInstitute of Environmental Science and Research Ltd, Porirua, The New ZealandInstitute of Environmental Science and Research Ltd, Porirua, The New ZealandInstitute of Environmental Science and Research Ltd, Porirua, The New ZealandInstitute of Environmental Science and Research Ltd, Porirua, The New ZealandInstitute of Environmental Science and Research Ltd, Porirua, The New ZealandInstitute of Environmental Science and Research Ltd, Porirua, The New ZealandMinistry of Health, Wellington, The New ZealandHawke`s Bay District Health Board, Napier, The New ZealandInstitute of Environmental Science and Research Ltd, Porirua, The New ZealandSchool of Health and Sport Science, Eastern Institute of Technology, Napier, The New ZealandObjectives In August 2016, Campylobacter spp contaminated an untreated reticulated water supply resulting in a large-scale gastroenteritis outbreak affecting an estimated 8320 people. We aimed to determine the incidence of probable reactive arthritis (ReA) cases in individuals with culture-confirmed campylobacteriosis (CC), self-reported probable campylobacteriosis (PC) and those reporting no diarrhoea (ND).Design We conducted a retrospective cohort study to identify incidence of probable ReA cases. We identified cases with new ReA symptoms using an adapted acute ReA (AReA) telephone questionnaire. Those reporting ≥1 symptom underwent a telephone interview with the study rheumatologist. Probable ReA was defined as spontaneous onset of pain suggestive of inflammatory arthritis in ≥1 previously asymptomatic joint for ≥3 days occurring ≤12 weeks after outbreak onset.Setting Population-based epidemiological study in Havelock North, New Zealand.Participants We enrolled notified CC cases with gastroenteritis symptom onsets 5 August 2016–6 September 2016 and conducted a telephone survey of households supplied by the contaminated water source to enrol PC and ND cases.Results One hundred and six (47.3%) CC, 47 (32.6%) PC and 113 (34.3%) ND cases completed the AReA telephone questionnaire. Of those reporting ≥1 new ReA symptom, 45 (75.0%) CC, 13 (68.4%) PC and 14 (82.4%) ND cases completed the rheumatologist telephone interview. Nineteen CC, 4 PC and 2 ND cases developed probable ReA, resulting in minimum incidences of 8.5%, 2.8% and 0.6% and maximum incidences of 23.9%, 12.4% and 2.15%.Discussion We describe high probable ReA incidences among gastroenteritis case types during a very large Campylobacter gastroenteritis outbreak using a resource-efficient method that is feasible to employ in future outbreaks.https://bmjopen.bmj.com/content/12/6/e060173.full |
| spellingShingle | Nicholas Jones Rebecca Grainger Michael G Baker Tim Wood Tiffany A Walker Terence Quirke Rebekah Roos Jill Sherwood Graham Mackereth Tomasz Kiedrzynski Rachel Eyre Shevaun Paine Anita Jagroop Reactive arthritis incidence in a community cohort following a large waterborne campylobacteriosis outbreak in Havelock North, New Zealand BMJ Open |
| title | Reactive arthritis incidence in a community cohort following a large waterborne campylobacteriosis outbreak in Havelock North, New Zealand |
| title_full | Reactive arthritis incidence in a community cohort following a large waterborne campylobacteriosis outbreak in Havelock North, New Zealand |
| title_fullStr | Reactive arthritis incidence in a community cohort following a large waterborne campylobacteriosis outbreak in Havelock North, New Zealand |
| title_full_unstemmed | Reactive arthritis incidence in a community cohort following a large waterborne campylobacteriosis outbreak in Havelock North, New Zealand |
| title_short | Reactive arthritis incidence in a community cohort following a large waterborne campylobacteriosis outbreak in Havelock North, New Zealand |
| title_sort | reactive arthritis incidence in a community cohort following a large waterborne campylobacteriosis outbreak in havelock north new zealand |
| url | https://bmjopen.bmj.com/content/12/6/e060173.full |
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