Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study
Dengue is one of the arthropod-borne (arbo) viral diseases transmitted by female mosquito Aedes aegypti. Dengue fever has a wide spectrum of clinical presentation ranging from flu-like illness to severe complicated stage of dengue hemorrhagic fever leading to mortality. This was a retrospective stud...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/647162 |
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| author | Ramakrishna Pai Jakribettu Rekha Boloor Andrew Thaliath Sharanya Yesudasan George Thomas George Manoj Ponadka Rai Umran Rafique Sheikh Kadke Shreedhara Avabratha Manjeshwar Shrinath Baliga |
| author_facet | Ramakrishna Pai Jakribettu Rekha Boloor Andrew Thaliath Sharanya Yesudasan George Thomas George Manoj Ponadka Rai Umran Rafique Sheikh Kadke Shreedhara Avabratha Manjeshwar Shrinath Baliga |
| author_sort | Ramakrishna Pai Jakribettu |
| collection | DOAJ |
| description | Dengue is one of the arthropod-borne (arbo) viral diseases transmitted by female mosquito Aedes aegypti. Dengue fever has a wide spectrum of clinical presentation ranging from flu-like illness to severe complicated stage of dengue hemorrhagic fever leading to mortality. This was a retrospective study conducted in a tertiary care hospital in Coastal Karnataka, South India, to know the correlation between the clinical presentation and haematological parameters in the paediatric cases presented with dengue symptoms. A total of 163 paediatric cases who presented fever and dengue-like illness were included in the study. Of which, 69 were confirmed dengue patients. Critical analysis showed that there was a significant difference in the haematological parameters like total leucocyte count, percent differential leucocyte count, and platelets count, in the erythrocyte sedimentation rate (P<0.05 to 0.0001). Additionally, when compared to nondengue patients, even the liver function and renal function parameters were significantly deranged (P<0.05 to 0.0001). Stratification based on NS1, IgG, and IgM showed significant alterations in the haematological, hepatic, and renal parameters. With respect to the treatment a small percentage of patients, that is, 8% (4 patients), required platelet transfusion as their counts went below 20,000/μL. Two patients succumbed to their illness while three required ICU stay. |
| format | Article |
| id | doaj-art-420695a8a64640aa9e85b51213ee7262 |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-420695a8a64640aa9e85b51213ee72622025-02-03T00:59:48ZengWileyJournal of Tropical Medicine1687-96861687-96942015-01-01201510.1155/2015/647162647162Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective StudyRamakrishna Pai Jakribettu0Rekha Boloor1Andrew Thaliath2Sharanya Yesudasan George3Thomas George4Manoj Ponadka Rai5Umran Rafique Sheikh6Kadke Shreedhara Avabratha7Manjeshwar Shrinath Baliga8Department of Microbiology, Father Muller Medical College, Kankanady, Mangalore, Karnataka 575002, IndiaDepartment of Microbiology, Father Muller Medical College, Kankanady, Mangalore, Karnataka 575002, IndiaFather Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, IndiaFather Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, IndiaFather Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, IndiaFather Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, IndiaFather Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, IndiaDepartment of Paediatrics, Father Muller Medical College, Kankanady, Mangalore, Karnataka 575002, IndiaFather Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, IndiaDengue is one of the arthropod-borne (arbo) viral diseases transmitted by female mosquito Aedes aegypti. Dengue fever has a wide spectrum of clinical presentation ranging from flu-like illness to severe complicated stage of dengue hemorrhagic fever leading to mortality. This was a retrospective study conducted in a tertiary care hospital in Coastal Karnataka, South India, to know the correlation between the clinical presentation and haematological parameters in the paediatric cases presented with dengue symptoms. A total of 163 paediatric cases who presented fever and dengue-like illness were included in the study. Of which, 69 were confirmed dengue patients. Critical analysis showed that there was a significant difference in the haematological parameters like total leucocyte count, percent differential leucocyte count, and platelets count, in the erythrocyte sedimentation rate (P<0.05 to 0.0001). Additionally, when compared to nondengue patients, even the liver function and renal function parameters were significantly deranged (P<0.05 to 0.0001). Stratification based on NS1, IgG, and IgM showed significant alterations in the haematological, hepatic, and renal parameters. With respect to the treatment a small percentage of patients, that is, 8% (4 patients), required platelet transfusion as their counts went below 20,000/μL. Two patients succumbed to their illness while three required ICU stay.http://dx.doi.org/10.1155/2015/647162 |
| spellingShingle | Ramakrishna Pai Jakribettu Rekha Boloor Andrew Thaliath Sharanya Yesudasan George Thomas George Manoj Ponadka Rai Umran Rafique Sheikh Kadke Shreedhara Avabratha Manjeshwar Shrinath Baliga Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study Journal of Tropical Medicine |
| title | Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
| title_full | Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
| title_fullStr | Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
| title_full_unstemmed | Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
| title_short | Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study |
| title_sort | correlation of clinicohaematological parameters in paediatric dengue a retrospective study |
| url | http://dx.doi.org/10.1155/2015/647162 |
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