Role of New Functional MRI Techniques in the Diagnosis, Staging, and Followup of Gynecological Cancer: Comparison with PET-CT

Recent developments in diagnostic imaging techniques have magnified the role and potential of both MRI and PET-CT in female pelvic imaging. This article reviews the techniques and clinical applications of new functional MRI (fMRI) including diffusion-weighted MRI (DWI), dynamic contrast-enhanced (DC...

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Main Authors: Elena Alvarez Moreno, Mar Jimenez de la Peña, Raquel Cano Alonso
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Radiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/219546
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author Elena Alvarez Moreno
Mar Jimenez de la Peña
Raquel Cano Alonso
author_facet Elena Alvarez Moreno
Mar Jimenez de la Peña
Raquel Cano Alonso
author_sort Elena Alvarez Moreno
collection DOAJ
description Recent developments in diagnostic imaging techniques have magnified the role and potential of both MRI and PET-CT in female pelvic imaging. This article reviews the techniques and clinical applications of new functional MRI (fMRI) including diffusion-weighted MRI (DWI), dynamic contrast-enhanced (DCE)-MRI, comparing with PET-CT. These new emerging provide not only anatomic but also functional imaging, allowing detection of small volumes of active tumor at diagnosis and early disease relapse, which may not result in detectable morphological changes at conventional imaging. This information is useful in distinguishing between recurrent/residual tumor and post-treatment changes and assessing treatment response, with a clear impact on patient management. Both PET-CT and now fMRI have proved to be very valuable tools for evaluation of gynecologic tumors. Most papers try to compare these techniques, but in our experience both are complementary in management of these patients. Meanwhile PET-CT is superior in diagnosis of ganglionar disease; fMRI presents higher accuracy in local preoperative staging. Both techniques can be used as biomarkers of tumor response and present high accuracy in diagnosis of local recurrence and peritoneal dissemination, with complementary roles depending on histological type, anatomic location and tumoral volume.
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spelling doaj-art-41f81772aa38460192514bcd6ae31f6b2025-02-03T05:43:38ZengWileyRadiology Research and Practice2090-19412090-195X2012-01-01201210.1155/2012/219546219546Role of New Functional MRI Techniques in the Diagnosis, Staging, and Followup of Gynecological Cancer: Comparison with PET-CTElena Alvarez Moreno0Mar Jimenez de la Peña1Raquel Cano Alonso2Department of Diagnostic Imaging, Hospital Quiron Madrid, Diego de Velázquez 1, 28223 Madrid, SpainDepartment of Diagnostic Imaging, Hospital Quiron Madrid, Diego de Velázquez 1, 28223 Madrid, SpainDepartment of Diagnostic Imaging, Hospital Quiron Madrid, Diego de Velázquez 1, 28223 Madrid, SpainRecent developments in diagnostic imaging techniques have magnified the role and potential of both MRI and PET-CT in female pelvic imaging. This article reviews the techniques and clinical applications of new functional MRI (fMRI) including diffusion-weighted MRI (DWI), dynamic contrast-enhanced (DCE)-MRI, comparing with PET-CT. These new emerging provide not only anatomic but also functional imaging, allowing detection of small volumes of active tumor at diagnosis and early disease relapse, which may not result in detectable morphological changes at conventional imaging. This information is useful in distinguishing between recurrent/residual tumor and post-treatment changes and assessing treatment response, with a clear impact on patient management. Both PET-CT and now fMRI have proved to be very valuable tools for evaluation of gynecologic tumors. Most papers try to compare these techniques, but in our experience both are complementary in management of these patients. Meanwhile PET-CT is superior in diagnosis of ganglionar disease; fMRI presents higher accuracy in local preoperative staging. Both techniques can be used as biomarkers of tumor response and present high accuracy in diagnosis of local recurrence and peritoneal dissemination, with complementary roles depending on histological type, anatomic location and tumoral volume.http://dx.doi.org/10.1155/2012/219546
spellingShingle Elena Alvarez Moreno
Mar Jimenez de la Peña
Raquel Cano Alonso
Role of New Functional MRI Techniques in the Diagnosis, Staging, and Followup of Gynecological Cancer: Comparison with PET-CT
Radiology Research and Practice
title Role of New Functional MRI Techniques in the Diagnosis, Staging, and Followup of Gynecological Cancer: Comparison with PET-CT
title_full Role of New Functional MRI Techniques in the Diagnosis, Staging, and Followup of Gynecological Cancer: Comparison with PET-CT
title_fullStr Role of New Functional MRI Techniques in the Diagnosis, Staging, and Followup of Gynecological Cancer: Comparison with PET-CT
title_full_unstemmed Role of New Functional MRI Techniques in the Diagnosis, Staging, and Followup of Gynecological Cancer: Comparison with PET-CT
title_short Role of New Functional MRI Techniques in the Diagnosis, Staging, and Followup of Gynecological Cancer: Comparison with PET-CT
title_sort role of new functional mri techniques in the diagnosis staging and followup of gynecological cancer comparison with pet ct
url http://dx.doi.org/10.1155/2012/219546
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AT marjimenezdelapena roleofnewfunctionalmritechniquesinthediagnosisstagingandfollowupofgynecologicalcancercomparisonwithpetct
AT raquelcanoalonso roleofnewfunctionalmritechniquesinthediagnosisstagingandfollowupofgynecologicalcancercomparisonwithpetct