Fragments of viral surface proteins modulate innate immune responses via formyl peptide receptors

Fragments of viral surface proteins modulate innate immune responses via formyl peptide receptors

Summary: Formyl peptide receptors (FPRs) are pattern recognition receptors well-known for bacterial pathogen sensing. We here identified activator and inhibitor motifs for FPRs that are present on surface proteins of various viral pathogens. Peptides containing these motifs interact with all FPR fam...

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Bibliographic Details
Main Authors: Heiko Heilmann, Lukas Busch, Celine Buchmann, Islam Mohamed, Adrian Theiß, Sabryna Junker, Stefan Lohse, Bernd Bufe
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
Subjects:
Immunity
Immune response
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225012805
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