Opportunity for early de-escalation of antibiotics in Enterobacterales bacteremia with multiplex PCR rapid diagnostic technology
Gram-negative bacteremia and antimicrobial resistance cause significant morbidity and mortality. Strategies are needed to optimize rapid and effective antimicrobial therapy with early de-escalation. In this brief, we describe the utilization of multiplex polymerase chain reaction rapid diagnostic te...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2025-01-01
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| Series: | Antimicrobial Stewardship & Healthcare Epidemiology |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2732494X24004881/type/journal_article |
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| author | Erin Deja Adam Greenfield Sangeeta Sastry Barry Rittmann |
| author_facet | Erin Deja Adam Greenfield Sangeeta Sastry Barry Rittmann |
| author_sort | Erin Deja |
| collection | DOAJ |
| description | Gram-negative bacteremia and antimicrobial resistance cause significant morbidity and mortality. Strategies are needed to optimize rapid and effective antimicrobial therapy with early de-escalation. In this brief, we describe the utilization of multiplex polymerase chain reaction rapid diagnostic technology for the early de-escalation of broad-spectrum antimicrobials in patients with Enterobacterales bacteremia. |
| format | Article |
| id | doaj-art-41f419ac29774b37977170fd7844530e |
| institution | Kabale University |
| issn | 2732-494X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Antimicrobial Stewardship & Healthcare Epidemiology |
| spelling | doaj-art-41f419ac29774b37977170fd7844530e2025-01-27T10:13:08ZengCambridge University PressAntimicrobial Stewardship & Healthcare Epidemiology2732-494X2025-01-01510.1017/ash.2024.488Opportunity for early de-escalation of antibiotics in Enterobacterales bacteremia with multiplex PCR rapid diagnostic technologyErin Deja0https://orcid.org/0009-0009-1199-6791Adam Greenfield1https://orcid.org/0000-0002-8417-9575Sangeeta Sastry2https://orcid.org/0009-0002-1342-8252Barry Rittmann3Department of Pharmacy, Virginia Commonwealth University Health System, Richmond, VA, USADepartment of Pharmacy, Virginia Commonwealth University Health System, Richmond, VA, USADepartment of Internal Medicine, Division of Infectious Diseases, Virginia Commonwealth University Health System, Richmond, VA, USADepartment of Internal Medicine, Division of Infectious Diseases, Virginia Commonwealth University Health System, Richmond, VA, USAGram-negative bacteremia and antimicrobial resistance cause significant morbidity and mortality. Strategies are needed to optimize rapid and effective antimicrobial therapy with early de-escalation. In this brief, we describe the utilization of multiplex polymerase chain reaction rapid diagnostic technology for the early de-escalation of broad-spectrum antimicrobials in patients with Enterobacterales bacteremia.https://www.cambridge.org/core/product/identifier/S2732494X24004881/type/journal_article |
| spellingShingle | Erin Deja Adam Greenfield Sangeeta Sastry Barry Rittmann Opportunity for early de-escalation of antibiotics in Enterobacterales bacteremia with multiplex PCR rapid diagnostic technology Antimicrobial Stewardship & Healthcare Epidemiology |
| title | Opportunity for early de-escalation of antibiotics in Enterobacterales bacteremia with multiplex PCR rapid diagnostic technology |
| title_full | Opportunity for early de-escalation of antibiotics in Enterobacterales bacteremia with multiplex PCR rapid diagnostic technology |
| title_fullStr | Opportunity for early de-escalation of antibiotics in Enterobacterales bacteremia with multiplex PCR rapid diagnostic technology |
| title_full_unstemmed | Opportunity for early de-escalation of antibiotics in Enterobacterales bacteremia with multiplex PCR rapid diagnostic technology |
| title_short | Opportunity for early de-escalation of antibiotics in Enterobacterales bacteremia with multiplex PCR rapid diagnostic technology |
| title_sort | opportunity for early de escalation of antibiotics in enterobacterales bacteremia with multiplex pcr rapid diagnostic technology |
| url | https://www.cambridge.org/core/product/identifier/S2732494X24004881/type/journal_article |
| work_keys_str_mv | AT erindeja opportunityforearlydeescalationofantibioticsinenterobacteralesbacteremiawithmultiplexpcrrapiddiagnostictechnology AT adamgreenfield opportunityforearlydeescalationofantibioticsinenterobacteralesbacteremiawithmultiplexpcrrapiddiagnostictechnology AT sangeetasastry opportunityforearlydeescalationofantibioticsinenterobacteralesbacteremiawithmultiplexpcrrapiddiagnostictechnology AT barryrittmann opportunityforearlydeescalationofantibioticsinenterobacteralesbacteremiawithmultiplexpcrrapiddiagnostictechnology |