Rhizomucor and Scedosporium Infection Post Hematopoietic Stem-Cell Transplant
Hematopoietic stem-cell transplant recipients are at increased risk of developing invasive fungal infections. This is a major cause of morbidity and mortality. We report a case of a 17-year-old male patient diagnosed with severe idiopathic acquired aplastic anemia who developed fungal pneumonitis du...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/830769 |
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| author | Dânia Sofia Marques Carlos Pinho Vaz Rosa Branca Fernando Campilho Catarina Lamelas Luis Pedro Afonso Manuel Jacome Eduardo Breda Eurico Monteiro António Campos Júnior |
| author_facet | Dânia Sofia Marques Carlos Pinho Vaz Rosa Branca Fernando Campilho Catarina Lamelas Luis Pedro Afonso Manuel Jacome Eduardo Breda Eurico Monteiro António Campos Júnior |
| author_sort | Dânia Sofia Marques |
| collection | DOAJ |
| description | Hematopoietic stem-cell transplant recipients are at increased risk of developing invasive fungal infections. This is a major cause of morbidity and mortality. We report a case of a 17-year-old male patient diagnosed with severe idiopathic acquired aplastic anemia who developed fungal pneumonitis due to Rhizomucor sp. and rhinoencephalitis due to Scedosporium apiospermum 6 and 8 months after undergoing allogeneic hematopoietic stem-cell transplant from an HLA-matched unrelated donor. Discussion highlights risk factors for invasive fungal infections (i.e., mucormycosis and scedosporiosis), its clinical features, and the factors that must be taken into account to successfully treat them (early diagnosis, correction of predisposing factors, aggressive surgical debridement, and antifungal and adjunctive therapies). |
| format | Article |
| id | doaj-art-41e5028453514fc783662f7ef0e11c44 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-41e5028453514fc783662f7ef0e11c442025-02-03T00:59:48ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/830769830769Rhizomucor and Scedosporium Infection Post Hematopoietic Stem-Cell TransplantDânia Sofia Marques0Carlos Pinho Vaz1Rosa Branca2Fernando Campilho3Catarina Lamelas4Luis Pedro Afonso5Manuel Jacome6Eduardo Breda7Eurico Monteiro8António Campos Júnior9Bone Marrow Transplantation Service, Instituto Português de Oncologia Francisco Gentil, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, PortugalBone Marrow Transplantation Service, Instituto Português de Oncologia Francisco Gentil, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, PortugalBone Marrow Transplantation Service, Instituto Português de Oncologia Francisco Gentil, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, PortugalBone Marrow Transplantation Service, Instituto Português de Oncologia Francisco Gentil, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, PortugalMicrobiology Service, Instituto Português de Oncologia Francisco Gentil, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, PortugalPathology Service, Instituto Português de Oncologia Francisco Gentil, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, PortugalPathology Service, Instituto Português de Oncologia Francisco Gentil, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, PortugalOtorhinolaringology Service, Instituto Português de Oncologia Francisco Gentil, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, PortugalOtorhinolaringology Service, Instituto Português de Oncologia Francisco Gentil, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, PortugalBone Marrow Transplantation Service, Instituto Português de Oncologia Francisco Gentil, Rua Dr. António Bernardino de Almeida, 4200-072 Porto, PortugalHematopoietic stem-cell transplant recipients are at increased risk of developing invasive fungal infections. This is a major cause of morbidity and mortality. We report a case of a 17-year-old male patient diagnosed with severe idiopathic acquired aplastic anemia who developed fungal pneumonitis due to Rhizomucor sp. and rhinoencephalitis due to Scedosporium apiospermum 6 and 8 months after undergoing allogeneic hematopoietic stem-cell transplant from an HLA-matched unrelated donor. Discussion highlights risk factors for invasive fungal infections (i.e., mucormycosis and scedosporiosis), its clinical features, and the factors that must be taken into account to successfully treat them (early diagnosis, correction of predisposing factors, aggressive surgical debridement, and antifungal and adjunctive therapies).http://dx.doi.org/10.1155/2011/830769 |
| spellingShingle | Dânia Sofia Marques Carlos Pinho Vaz Rosa Branca Fernando Campilho Catarina Lamelas Luis Pedro Afonso Manuel Jacome Eduardo Breda Eurico Monteiro António Campos Júnior Rhizomucor and Scedosporium Infection Post Hematopoietic Stem-Cell Transplant Case Reports in Medicine |
| title | Rhizomucor and Scedosporium Infection Post Hematopoietic Stem-Cell Transplant |
| title_full | Rhizomucor and Scedosporium Infection Post Hematopoietic Stem-Cell Transplant |
| title_fullStr | Rhizomucor and Scedosporium Infection Post Hematopoietic Stem-Cell Transplant |
| title_full_unstemmed | Rhizomucor and Scedosporium Infection Post Hematopoietic Stem-Cell Transplant |
| title_short | Rhizomucor and Scedosporium Infection Post Hematopoietic Stem-Cell Transplant |
| title_sort | rhizomucor and scedosporium infection post hematopoietic stem cell transplant |
| url | http://dx.doi.org/10.1155/2011/830769 |
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