Mitigating antimicrobial resistance through effective hospital wastewater management in low- and middle-income countries
Hospital wastewater (HWW) is a significant environmental and public health threat, containing high levels of pollutants such as antibiotic-resistant bacteria (ARB), antibiotic-resistant genes (ARGs), antibiotics, disinfectants, and heavy metals. This threat is of particular concern in low- and middl...
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Frontiers Media S.A.
2025-01-01
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| author | Yaovi Mahuton Gildas Hounmanou Yaovi Mahuton Gildas Hounmanou Adonias Houefonde I-CRECT Consortium Tram Thuy Nguyen Anders Dalsgaard Linh Viet Nguyen Tung Xuan Nguyen Troung Nhat My Lan Thi Le Huyen Thi Vu Ngoc Thi Bich Hoang Dien M. Tran Thi Anh Mai Pham Phuc D. Pham Dennis Nurjadi Flavie Goutard Thirumalaisamy P. Velavan Van Anh Thi Dinh Bent Jörgensen Le Huu Song Nhung T.T. Nguyen Etienne Loire Åse Östholm Lennart E. Nilsson Tuyet Hanh T. Tran Phuc H. Phan Mattias Larsson Linus Olson Håkan Hanberger |
| author_facet | Yaovi Mahuton Gildas Hounmanou Yaovi Mahuton Gildas Hounmanou Adonias Houefonde I-CRECT Consortium Tram Thuy Nguyen Anders Dalsgaard Linh Viet Nguyen Tung Xuan Nguyen Troung Nhat My Lan Thi Le Huyen Thi Vu Ngoc Thi Bich Hoang Dien M. Tran Thi Anh Mai Pham Phuc D. Pham Dennis Nurjadi Flavie Goutard Thirumalaisamy P. Velavan Van Anh Thi Dinh Bent Jörgensen Le Huu Song Nhung T.T. Nguyen Etienne Loire Åse Östholm Lennart E. Nilsson Tuyet Hanh T. Tran Phuc H. Phan Mattias Larsson Linus Olson Håkan Hanberger |
| author_sort | Yaovi Mahuton Gildas Hounmanou |
| collection | DOAJ |
| description | Hospital wastewater (HWW) is a significant environmental and public health threat, containing high levels of pollutants such as antibiotic-resistant bacteria (ARB), antibiotic-resistant genes (ARGs), antibiotics, disinfectants, and heavy metals. This threat is of particular concern in low- and middle-income countries (LMICs), where untreated effluents are often used for irrigating vegetables crops, leading to direct and indirect human exposure. Despite being a potential hotspot for the spread of antimicrobial resistance (AMR), existing HWW treatment systems in LMICs primarily target conventional pollutants and lack effective standards for monitoring the removal of ARB and ARGs. Consequently, untreated or inadequately treated HWW continues to disseminate ARB and ARGs, exacerbating the risk of AMR proliferation. Addressing this requires targeted interventions, including cost-effective treatment solutions, robust AMR monitoring protocols, and policy-driven strategies tailored to LMICs. This perspective calls for a paradigm shift in HWW management in LMIC, emphasizing the broader implementation of onsite treatment systems, which are currently rare. Key recommendations include developing affordable and contextually adaptable technologies for eliminating ARB and ARGs and enforcing local regulations for AMR monitoring and control in wastewater. Addressing these challenges is essential for protecting public health, preventing the environmental spread of resistance, and contributing to a global effort to preserve the efficacy of antibiotics. Recommendations include integrating scalable onsite technologies, leveraging local knowledge, and implementing comprehensive AMR-focused regulatory frameworks. |
| format | Article |
| id | doaj-art-41d26dbdcb164f45a24adf44495b35ea |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Public Health |
| spelling | doaj-art-41d26dbdcb164f45a24adf44495b35ea2025-01-29T14:46:24ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-01-011210.3389/fpubh.2024.15258731525873Mitigating antimicrobial resistance through effective hospital wastewater management in low- and middle-income countriesYaovi Mahuton Gildas Hounmanou0Yaovi Mahuton Gildas Hounmanou1Adonias Houefonde2I-CRECT ConsortiumTram Thuy Nguyen3Anders Dalsgaard4Linh Viet NguyenTung Xuan NguyenTroung Nhat MyLan Thi LeHuyen Thi VuNgoc Thi Bich HoangDien M. TranThi Anh Mai PhamPhuc D. PhamDennis NurjadiFlavie GoutardThirumalaisamy P. VelavanVan Anh Thi DinhBent JörgensenLe Huu SongNhung T.T. NguyenEtienne LoireÅse ÖstholmLennart E. NilssonTuyet Hanh T. TranPhuc H. PhanMattias LarssonLinus OlsonHåkan HanbergerDepartment of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, DenmarkPolytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, BeninPolytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, BeninThe National Institute of Hygiene and Epidemiology (NIHE), Hanoi, VietnamDepartment of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, DenmarkHospital wastewater (HWW) is a significant environmental and public health threat, containing high levels of pollutants such as antibiotic-resistant bacteria (ARB), antibiotic-resistant genes (ARGs), antibiotics, disinfectants, and heavy metals. This threat is of particular concern in low- and middle-income countries (LMICs), where untreated effluents are often used for irrigating vegetables crops, leading to direct and indirect human exposure. Despite being a potential hotspot for the spread of antimicrobial resistance (AMR), existing HWW treatment systems in LMICs primarily target conventional pollutants and lack effective standards for monitoring the removal of ARB and ARGs. Consequently, untreated or inadequately treated HWW continues to disseminate ARB and ARGs, exacerbating the risk of AMR proliferation. Addressing this requires targeted interventions, including cost-effective treatment solutions, robust AMR monitoring protocols, and policy-driven strategies tailored to LMICs. This perspective calls for a paradigm shift in HWW management in LMIC, emphasizing the broader implementation of onsite treatment systems, which are currently rare. Key recommendations include developing affordable and contextually adaptable technologies for eliminating ARB and ARGs and enforcing local regulations for AMR monitoring and control in wastewater. Addressing these challenges is essential for protecting public health, preventing the environmental spread of resistance, and contributing to a global effort to preserve the efficacy of antibiotics. Recommendations include integrating scalable onsite technologies, leveraging local knowledge, and implementing comprehensive AMR-focused regulatory frameworks.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1525873/fullhospital wastewaterantimicrobial resistanceantibiotic-resistant genesantibioticresistant bacteriahospital wastewater management |
| spellingShingle | Yaovi Mahuton Gildas Hounmanou Yaovi Mahuton Gildas Hounmanou Adonias Houefonde I-CRECT Consortium Tram Thuy Nguyen Anders Dalsgaard Linh Viet Nguyen Tung Xuan Nguyen Troung Nhat My Lan Thi Le Huyen Thi Vu Ngoc Thi Bich Hoang Dien M. Tran Thi Anh Mai Pham Phuc D. Pham Dennis Nurjadi Flavie Goutard Thirumalaisamy P. Velavan Van Anh Thi Dinh Bent Jörgensen Le Huu Song Nhung T.T. Nguyen Etienne Loire Åse Östholm Lennart E. Nilsson Tuyet Hanh T. Tran Phuc H. Phan Mattias Larsson Linus Olson Håkan Hanberger Mitigating antimicrobial resistance through effective hospital wastewater management in low- and middle-income countries Frontiers in Public Health hospital wastewater antimicrobial resistance antibiotic-resistant genes antibioticresistant bacteria hospital wastewater management |
| title | Mitigating antimicrobial resistance through effective hospital wastewater management in low- and middle-income countries |
| title_full | Mitigating antimicrobial resistance through effective hospital wastewater management in low- and middle-income countries |
| title_fullStr | Mitigating antimicrobial resistance through effective hospital wastewater management in low- and middle-income countries |
| title_full_unstemmed | Mitigating antimicrobial resistance through effective hospital wastewater management in low- and middle-income countries |
| title_short | Mitigating antimicrobial resistance through effective hospital wastewater management in low- and middle-income countries |
| title_sort | mitigating antimicrobial resistance through effective hospital wastewater management in low and middle income countries |
| topic | hospital wastewater antimicrobial resistance antibiotic-resistant genes antibioticresistant bacteria hospital wastewater management |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1525873/full |
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