Validation of a potency assay for CD34 + cell based therapy

Abstract ProtheraCytes (expanded autologous CD34 + cells) promote regeneration by revascularising damaged myocardial tissue via angiogenesis through the secretion of vascular endothelium growth factor (VEGF). We developed a potency assay based on the quantification of the secreted VEGF during the ex...

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Bibliographic Details
Main Authors: Christine Vignon, Arthur Cormier, Aurélien Goubaud, Hélène Schaffhauser, Sara Bennaoum, Eva Grotzinger, Jean-Olivier Hirsch, Philippe Hénon, Matthieu de Kalbermatten, Ibon Garitaonandia
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-14828-w
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