Youthful Stem Cell Microenvironments: Rejuvenating Aged Bone Repair Through Mitochondrial Homeostasis Remodeling

Youthful Stem Cell Microenvironments: Rejuvenating Aged Bone Repair Through Mitochondrial Homeostasis Remodeling

Abstract Extracellular matrix (ECM) derived from mesenchymal stem cells regulates antioxidant properties and bone metabolism by providing a favorable extracellular microenvironment. However, its functional role and molecular mechanism in mitochondrial function regulation and aged bone regeneration r...

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Bibliographic Details
Main Authors:	Xinfeng Zhou, Xin Tian, Jianan Chen, Yantong Li, Nanning Lv, Hao Liu, Tao Liu, Huilin Yang, Xi Chen, Yong Xu, Fan He
Format:	Article
Language:	English
Published:	Wiley 2025-03-01
Series:	Advanced Science
Subjects:	aged bone defects bone marrow‐derived mesenchymal stem cells mitochondrial energy metabolism SIRT3 youthful extracellular matrix
Online Access:	https://doi.org/10.1002/advs.202409644
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