Massive Pleural Effusion in an 18-Year-Old Girl with Ewing Sarcoma

Ewing sarcoma is a bone tumour that commonly appears between ages five and 10 in the diaphysis of the long bones and predominantly presents with pain and swelling. The case of an 18-year-old girl who presented with back pain, cough, dyspnea, weakness and fever is described. Chest radiograph showed a...

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Main Authors: Cengiz Özge, Mukadder Çalikoglu, Leyla Cinel, F Demir Apaydin, Eylem S Özgür
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2004/103637
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author Cengiz Özge
Mukadder Çalikoglu
Leyla Cinel
F Demir Apaydin
Eylem S Özgür
author_facet Cengiz Özge
Mukadder Çalikoglu
Leyla Cinel
F Demir Apaydin
Eylem S Özgür
author_sort Cengiz Özge
collection DOAJ
description Ewing sarcoma is a bone tumour that commonly appears between ages five and 10 in the diaphysis of the long bones and predominantly presents with pain and swelling. The case of an 18-year-old girl who presented with back pain, cough, dyspnea, weakness and fever is described. Chest radiograph showed a homogenous density in the middle and inferior zones of the right hemithorax. Thoracic computed tomography revealed a diffuse pleural effusion and a 6.99 cmx4.45 cm solid mass composed of lobulated, small cystic lesions and calcifications in the right hemithorax. Biochemical analysis of pleural fluid showed hemorrhagic effusion and exudate. A pleural needle biopsy demonstrated solid uniform tumour cells with narrowed cytoplasm, round nuclei and uncertain nucleoli. All of the tumour cell cytoplasms stained with CD99. The pathological examination supported Ewing sarcoma. Three-phase Tc-99m methylene diphosphonate scintigraphy of the whole body showed pathological tracer uptake in a broad area of the eighth costal bone and in smaller areas of the ninth and 10th costal bones. This case is reported because Ewing sarcoma is a rare cause of pleural effusion in clinical practice among younger adults.
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spelling doaj-art-41a61eee816d41d6b656cf8587900e7b2025-02-03T01:01:35ZengWileyCanadian Respiratory Journal1198-22412004-01-0111536336510.1155/2004/103637Massive Pleural Effusion in an 18-Year-Old Girl with Ewing SarcomaCengiz ÖzgeMukadder ÇalikogluLeyla CinelF Demir ApaydinEylem S ÖzgürEwing sarcoma is a bone tumour that commonly appears between ages five and 10 in the diaphysis of the long bones and predominantly presents with pain and swelling. The case of an 18-year-old girl who presented with back pain, cough, dyspnea, weakness and fever is described. Chest radiograph showed a homogenous density in the middle and inferior zones of the right hemithorax. Thoracic computed tomography revealed a diffuse pleural effusion and a 6.99 cmx4.45 cm solid mass composed of lobulated, small cystic lesions and calcifications in the right hemithorax. Biochemical analysis of pleural fluid showed hemorrhagic effusion and exudate. A pleural needle biopsy demonstrated solid uniform tumour cells with narrowed cytoplasm, round nuclei and uncertain nucleoli. All of the tumour cell cytoplasms stained with CD99. The pathological examination supported Ewing sarcoma. Three-phase Tc-99m methylene diphosphonate scintigraphy of the whole body showed pathological tracer uptake in a broad area of the eighth costal bone and in smaller areas of the ninth and 10th costal bones. This case is reported because Ewing sarcoma is a rare cause of pleural effusion in clinical practice among younger adults.http://dx.doi.org/10.1155/2004/103637
spellingShingle Cengiz Özge
Mukadder Çalikoglu
Leyla Cinel
F Demir Apaydin
Eylem S Özgür
Massive Pleural Effusion in an 18-Year-Old Girl with Ewing Sarcoma
Canadian Respiratory Journal
title Massive Pleural Effusion in an 18-Year-Old Girl with Ewing Sarcoma
title_full Massive Pleural Effusion in an 18-Year-Old Girl with Ewing Sarcoma
title_fullStr Massive Pleural Effusion in an 18-Year-Old Girl with Ewing Sarcoma
title_full_unstemmed Massive Pleural Effusion in an 18-Year-Old Girl with Ewing Sarcoma
title_short Massive Pleural Effusion in an 18-Year-Old Girl with Ewing Sarcoma
title_sort massive pleural effusion in an 18 year old girl with ewing sarcoma
url http://dx.doi.org/10.1155/2004/103637
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AT leylacinel massivepleuraleffusioninan18yearoldgirlwithewingsarcoma
AT fdemirapaydin massivepleuraleffusioninan18yearoldgirlwithewingsarcoma
AT eylemsozgur massivepleuraleffusioninan18yearoldgirlwithewingsarcoma