Tailored amination enables switchable synthesis of α- and γ-amino acid derivatives from extended quinone methides
Abstract Unnatural α- and γ-amino acids display a diverse range of biological activities and serve as crucial intermediates in pharmaceutical production. Specifically, the synthesis of such molecules has been highly sought after in both academia and industry. Nevertheless, their direct synthesis fro...
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| Main Authors: | Chao-Gang Zhang, Yu-Ping Tang, Qingqin Huang, Yong-Ke Qiu, Hailong Yan, Lei Dai |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-60749-7 |
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