Engineering the TetR-family transcriptional regulator XNR_0706 to enhance heterologous spinosad production in Streptomyces albus B4 chassis

Engineering the TetR-family transcriptional regulator XNR_0706 to enhance heterologous spinosad production in Streptomyces albus B4 chassis

The TetR family of regulators are an important group of transcription regulators that regulate diverse cellular processes in prokaryotes. In this study, we found that XNR_0706, a TetR family regulator, controlled the expression of XNR_0345, XNR_0454, XNR_0513 and XNR_1438 putatively involved in fatt...

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Bibliographic Details
Main Authors:	Xingjun Cui, Hao Tang, Wenzong Wang, Wenping Wei, Jing Wu, Bang-Ce Ye
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2025-03-01
Series:	Synthetic and Systems Biotechnology
Subjects:	Streptomyces albus B4 TetR family transcriptional regulator Spinosad Precursor supply Fatty acids metabolism Heterologous expression
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405805X24001194
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