Mycetoma Caused by Acremonium Species in a Patient with Chronic Granulomatous Disease

Patients with chronic granulomatous disease are predisposed to fungal infections and are therefore routinely prescribed antifungal prophylaxis. We report a case where acremonium was responsible for causing a cutaneous infection (mycetoma) despite antifungal prophylaxis. Treatment with voriconazole w...

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Main Authors: Richard Antrobus, Gabriel Wong, Julie Jones, Aarnoud Huissoon
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Immunology
Online Access:http://dx.doi.org/10.1155/2016/3209493
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author Richard Antrobus
Gabriel Wong
Julie Jones
Aarnoud Huissoon
author_facet Richard Antrobus
Gabriel Wong
Julie Jones
Aarnoud Huissoon
author_sort Richard Antrobus
collection DOAJ
description Patients with chronic granulomatous disease are predisposed to fungal infections and are therefore routinely prescribed antifungal prophylaxis. We report a case where acremonium was responsible for causing a cutaneous infection (mycetoma) despite antifungal prophylaxis. Treatment with voriconazole was initiated and the infection gradually resolved. This case highlights the need for careful clinical follow-up and thorough investigation of patients who have a neutrophil immunodeficiency.
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institution Kabale University
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spelling doaj-art-416e796450e94f3088601a2b8cdef3492025-02-03T01:31:40ZengWileyCase Reports in Immunology2090-66092090-66172016-01-01201610.1155/2016/32094933209493Mycetoma Caused by Acremonium Species in a Patient with Chronic Granulomatous DiseaseRichard Antrobus0Gabriel Wong1Julie Jones2Aarnoud Huissoon3Department of Immunology, Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UKDepartment of Immunology, Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UKDepartment of Immunology, Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UKDepartment of Immunology, Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UKPatients with chronic granulomatous disease are predisposed to fungal infections and are therefore routinely prescribed antifungal prophylaxis. We report a case where acremonium was responsible for causing a cutaneous infection (mycetoma) despite antifungal prophylaxis. Treatment with voriconazole was initiated and the infection gradually resolved. This case highlights the need for careful clinical follow-up and thorough investigation of patients who have a neutrophil immunodeficiency.http://dx.doi.org/10.1155/2016/3209493
spellingShingle Richard Antrobus
Gabriel Wong
Julie Jones
Aarnoud Huissoon
Mycetoma Caused by Acremonium Species in a Patient with Chronic Granulomatous Disease
Case Reports in Immunology
title Mycetoma Caused by Acremonium Species in a Patient with Chronic Granulomatous Disease
title_full Mycetoma Caused by Acremonium Species in a Patient with Chronic Granulomatous Disease
title_fullStr Mycetoma Caused by Acremonium Species in a Patient with Chronic Granulomatous Disease
title_full_unstemmed Mycetoma Caused by Acremonium Species in a Patient with Chronic Granulomatous Disease
title_short Mycetoma Caused by Acremonium Species in a Patient with Chronic Granulomatous Disease
title_sort mycetoma caused by acremonium species in a patient with chronic granulomatous disease
url http://dx.doi.org/10.1155/2016/3209493
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AT gabrielwong mycetomacausedbyacremoniumspeciesinapatientwithchronicgranulomatousdisease
AT juliejones mycetomacausedbyacremoniumspeciesinapatientwithchronicgranulomatousdisease
AT aarnoudhuissoon mycetomacausedbyacremoniumspeciesinapatientwithchronicgranulomatousdisease