Rheumatic Fever Associated with Antiphospholipid Syndrome: Systematic Review

Objective. To evaluate the clinical associations between rheumatic fever and antiphospholipid syndrome and the impact of coexistence of these two diseases in an individual. Methods. Systematic review in electronics databases, regarding the period from 1983 to 2012. The keywords: “Rheumatic Fever,” “...

Full description

Saved in:
Bibliographic Details
Main Authors: Felipe da Silva, Jozélio de Carvalho
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2014/614591
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832555104221265920
author Felipe da Silva
Jozélio de Carvalho
author_facet Felipe da Silva
Jozélio de Carvalho
author_sort Felipe da Silva
collection DOAJ
description Objective. To evaluate the clinical associations between rheumatic fever and antiphospholipid syndrome and the impact of coexistence of these two diseases in an individual. Methods. Systematic review in electronics databases, regarding the period from 1983 to 2012. The keywords: “Rheumatic Fever,” “Antiphospholipid Syndrome,” and “Antiphospholipid Antibody Syndrome” are used. Results. were identified 11 cases described in the literature about the association of rheumatic fever and antiphospholipid syndrome. Clinical presentation of rheumatic fever was characterized by the predominance of carditis (11/11) and chorea (7/11). Regarding the manifestations of APS, the stroke was observed in 7/11 (63.6%), with one of them having probable embolic origin. Conclusion. The present study brings the information that the association between APS and RF is quite rare, however, is of great clinical importance. Doctors who deal with the RF should include in their differential diagnosis the APS, especially in the presence of stroke in patients with RF and whose echocardiogram does not show intracavitary thrombi.
format Article
id doaj-art-414fbf1c346e4f4abc93f6424251bb69
institution Kabale University
issn 2314-8861
2314-7156
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Journal of Immunology Research
spelling doaj-art-414fbf1c346e4f4abc93f6424251bb692025-02-03T05:49:35ZengWileyJournal of Immunology Research2314-88612314-71562014-01-01201410.1155/2014/614591614591Rheumatic Fever Associated with Antiphospholipid Syndrome: Systematic ReviewFelipe da Silva0Jozélio de Carvalho1Escola Bahiana de Medicina e Saúde Pública, 41810080 Salvador, BA, BrazilRheumatology Division, Centro Médico do Hospital Aliança, Rua das Violetas 42, AP. 502, 41810080 Salvador, BA, BrazilObjective. To evaluate the clinical associations between rheumatic fever and antiphospholipid syndrome and the impact of coexistence of these two diseases in an individual. Methods. Systematic review in electronics databases, regarding the period from 1983 to 2012. The keywords: “Rheumatic Fever,” “Antiphospholipid Syndrome,” and “Antiphospholipid Antibody Syndrome” are used. Results. were identified 11 cases described in the literature about the association of rheumatic fever and antiphospholipid syndrome. Clinical presentation of rheumatic fever was characterized by the predominance of carditis (11/11) and chorea (7/11). Regarding the manifestations of APS, the stroke was observed in 7/11 (63.6%), with one of them having probable embolic origin. Conclusion. The present study brings the information that the association between APS and RF is quite rare, however, is of great clinical importance. Doctors who deal with the RF should include in their differential diagnosis the APS, especially in the presence of stroke in patients with RF and whose echocardiogram does not show intracavitary thrombi.http://dx.doi.org/10.1155/2014/614591
spellingShingle Felipe da Silva
Jozélio de Carvalho
Rheumatic Fever Associated with Antiphospholipid Syndrome: Systematic Review
Journal of Immunology Research
title Rheumatic Fever Associated with Antiphospholipid Syndrome: Systematic Review
title_full Rheumatic Fever Associated with Antiphospholipid Syndrome: Systematic Review
title_fullStr Rheumatic Fever Associated with Antiphospholipid Syndrome: Systematic Review
title_full_unstemmed Rheumatic Fever Associated with Antiphospholipid Syndrome: Systematic Review
title_short Rheumatic Fever Associated with Antiphospholipid Syndrome: Systematic Review
title_sort rheumatic fever associated with antiphospholipid syndrome systematic review
url http://dx.doi.org/10.1155/2014/614591
work_keys_str_mv AT felipedasilva rheumaticfeverassociatedwithantiphospholipidsyndromesystematicreview
AT jozeliodecarvalho rheumaticfeverassociatedwithantiphospholipidsyndromesystematicreview