Acute Brucellosis Presenting as an Autoimmune Hemolytic Anemia

Brucellosis is one of the most widespread zoonosis in the world. Hematological complications in brucellosis usually present as mild anemia, leukopenia, or pancytopenia. Autoimmune hemolytic anemia in brucellosis is rarely reported. Here, we report an 18-year-old female presented to us with progressi...

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Main Authors: Durga Shankar Meena, Vikram Singh Sonwal, Amit Kumar Rohila, Vasudha Meena
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2018/1030382
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author Durga Shankar Meena
Vikram Singh Sonwal
Amit Kumar Rohila
Vasudha Meena
author_facet Durga Shankar Meena
Vikram Singh Sonwal
Amit Kumar Rohila
Vasudha Meena
author_sort Durga Shankar Meena
collection DOAJ
description Brucellosis is one of the most widespread zoonosis in the world. Hematological complications in brucellosis usually present as mild anemia, leukopenia, or pancytopenia. Autoimmune hemolytic anemia in brucellosis is rarely reported. Here, we report an 18-year-old female presented to us with progressive fatigue, jaundice, and fever. Hematological investigations revealed hemolytic anemia. Direct Coombs test was positive. Further evaluation showed positive serology and culture for Brucella. The patient was diagnosed with brucellosis with autoimmune hemolytic anemia. She was put on rifampicin and doxycycline along with corticosteroids. After 6 weeks, the patient was symptomatically improved with complete remission of hemolytic anemia. The possibility of brucellosis should be considered as a differential diagnosis of autoimmune hemolytic anemia, especially those living in the endemic areas.
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institution Kabale University
issn 2090-6625
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language English
publishDate 2018-01-01
publisher Wiley
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series Case Reports in Infectious Diseases
spelling doaj-art-4137869619e84b94beb4c8388ad4d3582025-02-03T05:51:40ZengWileyCase Reports in Infectious Diseases2090-66252090-66332018-01-01201810.1155/2018/10303821030382Acute Brucellosis Presenting as an Autoimmune Hemolytic AnemiaDurga Shankar Meena0Vikram Singh Sonwal1Amit Kumar Rohila2Vasudha Meena3Department of General Medicine, All India Institute of Medical Sciences, Jodhpur, IndiaDepartment of General Medicine, All India Institute of Medical Sciences, Jodhpur, IndiaDepartment of General Medicine, All India Institute of Medical Sciences, Jodhpur, IndiaDepartment of Pediatrics, SN Medical College, Jodhpur, IndiaBrucellosis is one of the most widespread zoonosis in the world. Hematological complications in brucellosis usually present as mild anemia, leukopenia, or pancytopenia. Autoimmune hemolytic anemia in brucellosis is rarely reported. Here, we report an 18-year-old female presented to us with progressive fatigue, jaundice, and fever. Hematological investigations revealed hemolytic anemia. Direct Coombs test was positive. Further evaluation showed positive serology and culture for Brucella. The patient was diagnosed with brucellosis with autoimmune hemolytic anemia. She was put on rifampicin and doxycycline along with corticosteroids. After 6 weeks, the patient was symptomatically improved with complete remission of hemolytic anemia. The possibility of brucellosis should be considered as a differential diagnosis of autoimmune hemolytic anemia, especially those living in the endemic areas.http://dx.doi.org/10.1155/2018/1030382
spellingShingle Durga Shankar Meena
Vikram Singh Sonwal
Amit Kumar Rohila
Vasudha Meena
Acute Brucellosis Presenting as an Autoimmune Hemolytic Anemia
Case Reports in Infectious Diseases
title Acute Brucellosis Presenting as an Autoimmune Hemolytic Anemia
title_full Acute Brucellosis Presenting as an Autoimmune Hemolytic Anemia
title_fullStr Acute Brucellosis Presenting as an Autoimmune Hemolytic Anemia
title_full_unstemmed Acute Brucellosis Presenting as an Autoimmune Hemolytic Anemia
title_short Acute Brucellosis Presenting as an Autoimmune Hemolytic Anemia
title_sort acute brucellosis presenting as an autoimmune hemolytic anemia
url http://dx.doi.org/10.1155/2018/1030382
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