Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma

Purpose. To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe. Method. AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We com...

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Main Authors: Wakako Ikegawa, Takashi Suzuki, Koji Namiguchi, Shiro Mizoue, Atsushi Shiraishi, Yuichi Ohashi
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2016/8496201
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author Wakako Ikegawa
Takashi Suzuki
Koji Namiguchi
Shiro Mizoue
Atsushi Shiraishi
Yuichi Ohashi
author_facet Wakako Ikegawa
Takashi Suzuki
Koji Namiguchi
Shiro Mizoue
Atsushi Shiraishi
Yuichi Ohashi
author_sort Wakako Ikegawa
collection DOAJ
description Purpose. To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe. Method. AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We compared the following AS parameters: anterior chamber depth (ACD), anterior chamber volume (ACV), iris curvature (IC), iris thickness at 500 μm from the scleral spur (IT-1) in the middle between the iris root and pupillary margin (IT-2) and 500 μm from the pupillary margin (IT-3) to the anterior chamber angle (ACA) (angle opening distance [AOD750]), and trabecular iris space area. Results. Mean IT-1 and IT-3, but not IT-2, were lower after iris bombe (IT-1, P=0.001; IT-2, P=0.081; and IT-3, P=0.001). There were no significant differences between ACD at pre-LPI and before iris bombe (P=0.096). The mean ACV and AOD750 of iris bombe increased at post-LPI (ACV, P<0.01, and AOD750, P<0.05). The mean IT-1, IT-2, and IT-3 increased at post-LPI (all, P≤0.01). IC decreased at post-LPI (P<0.001), and ACD at post-LPI did not change. Conclusions. The iris extends and becomes thinner during iris bombe. LPI during bombe decreases the IC and increases the ACV and ACA.
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spelling doaj-art-40df951efa5c4377857364962e79fdb02025-02-03T01:32:55ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/84962018496201Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary GlaucomaWakako Ikegawa0Takashi Suzuki1Koji Namiguchi2Shiro Mizoue3Atsushi Shiraishi4Yuichi Ohashi5Department of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, JapanDepartment of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, JapanDepartment of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, JapanDepartment of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, JapanDepartment of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, JapanDepartment of Ophthalmology, Graduate School of Medicine, Ehime University, Toon, Ehime 791-0295, JapanPurpose. To quantify changes in anterior segment (AS) parameters after laser peripheral iridotomy (LPI) using AS-optical coherence tomography (OCT) of iris bombe. Method. AS images of eight eyes were captured before and after iris bombe and more than 2 weeks after LPI (post-LPI) using AS-OCT. We compared the following AS parameters: anterior chamber depth (ACD), anterior chamber volume (ACV), iris curvature (IC), iris thickness at 500 μm from the scleral spur (IT-1) in the middle between the iris root and pupillary margin (IT-2) and 500 μm from the pupillary margin (IT-3) to the anterior chamber angle (ACA) (angle opening distance [AOD750]), and trabecular iris space area. Results. Mean IT-1 and IT-3, but not IT-2, were lower after iris bombe (IT-1, P=0.001; IT-2, P=0.081; and IT-3, P=0.001). There were no significant differences between ACD at pre-LPI and before iris bombe (P=0.096). The mean ACV and AOD750 of iris bombe increased at post-LPI (ACV, P<0.01, and AOD750, P<0.05). The mean IT-1, IT-2, and IT-3 increased at post-LPI (all, P≤0.01). IC decreased at post-LPI (P<0.001), and ACD at post-LPI did not change. Conclusions. The iris extends and becomes thinner during iris bombe. LPI during bombe decreases the IC and increases the ACV and ACA.http://dx.doi.org/10.1155/2016/8496201
spellingShingle Wakako Ikegawa
Takashi Suzuki
Koji Namiguchi
Shiro Mizoue
Atsushi Shiraishi
Yuichi Ohashi
Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma
Journal of Ophthalmology
title Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma
title_full Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma
title_fullStr Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma
title_full_unstemmed Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma
title_short Changes in Anterior Segment Morphology of Iris Bombe before and after Laser Peripheral Iridotomy in Patients with Uveitic Secondary Glaucoma
title_sort changes in anterior segment morphology of iris bombe before and after laser peripheral iridotomy in patients with uveitic secondary glaucoma
url http://dx.doi.org/10.1155/2016/8496201
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