Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years

Objective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Parti...

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Main Authors: Christos Grigoroglou, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Salwa S Zghebi, Rosa Parisi, Brian McMillan
Format: Article
Language:English
Published: BMJ Publishing Group 2022-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/7/e051456.full
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author Christos Grigoroglou
Darren M Ashcroft
Evangelos Kontopantelis
David Reeves
Salwa S Zghebi
Rosa Parisi
Brian McMillan
author_facet Christos Grigoroglou
Darren M Ashcroft
Evangelos Kontopantelis
David Reeves
Salwa S Zghebi
Rosa Parisi
Brian McMillan
author_sort Christos Grigoroglou
collection DOAJ
description Objective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Participants Patients with clinical codes for at least one of asthma, chronic obstructive pulmonary disease, diabetes, hypertension (HT), coronary heart disease, atrial fibrillation (AF), heart failure, stroke, hypothyroidism, chronic kidney disease, learning disability (LD), depression, dementia, epilepsy, severe mental illness (SMI), osteoarthritis, osteoporosis and cancer.Primary and secondary outcome measures For the frequency ranking of clinical codes, canonical correlation analysis was applied to correlations of clinical code usage of 1, 3 and 5 years. Three measures of diversity (Shannon entropy index of diversity, richness and evenness) were used to quantify changes in incident and total clinical codes.Results Overall, all examined conditions, except LD, showed positive monotonic correlation. HT, hypothyroidism, osteoarthritis and SMI codes’ usage had high 5-year correlation. The codes’ usage diversity remained stable overall throughout the study period. Cancer, diabetes and SMI had the highest richness (code lists need time to define) unlike AF, hypothyroidism and LD. SMI (high richness) and hypothyroidism (low richness) can last for 5 years, whereas cancer and diabetes (high richness) and LD (low richness) only last for 2 years.Conclusions This is an under-reported research area and the findings suggest the codes’ usage diversity for most conditions remained overall stable throughout the study period. Generated mental health code lists can last for a long time unlike cardiometabolic conditions and cancer. Adopting more consistent and less diverse coding would help improve data quality in primary care. Future research is needed following the transfer to the Systematised Nomenclature of Medicine Clinical Terms (SNOMED CT) coding.
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spelling doaj-art-40bc5bf2cebd474293abc374224e3c7a2025-01-31T09:30:09ZengBMJ Publishing GroupBMJ Open2044-60552022-07-0112710.1136/bmjopen-2021-051456Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 yearsChristos Grigoroglou0Darren M Ashcroft1Evangelos Kontopantelis2David Reeves3Salwa S Zghebi4Rosa Parisi5Brian McMillan61 Manchester Centre for Health Economics, Division of Population Health, Health Services Research and Primary Care, The University of Manchester, Manchester, UK2Division of Pharmacy and Optometry, Faculty of Biology Medicine and Health, University of ManchesterDivision of Informatics, Imaging, and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre (MAHSC), The University of Manchester, Manchester, UK3 Centre for Primary Care, University of Manchester, Manchester, UK4 Division of Population Health, Health Services Research and Primary Care; School of Health Sciences; Faculty of Biology, Medicine and Health; Manchester Academic Health Science Centre (MAHSC), The University of Manchester, Manchester, UKNIHR School for Primary Care Research, Centre for Primary Care and Health Services Research, Manchester Academic Health Science Centre (MAHSC), The University of Manchester, Manchester, UKsenior clinical lecturerObjective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Participants Patients with clinical codes for at least one of asthma, chronic obstructive pulmonary disease, diabetes, hypertension (HT), coronary heart disease, atrial fibrillation (AF), heart failure, stroke, hypothyroidism, chronic kidney disease, learning disability (LD), depression, dementia, epilepsy, severe mental illness (SMI), osteoarthritis, osteoporosis and cancer.Primary and secondary outcome measures For the frequency ranking of clinical codes, canonical correlation analysis was applied to correlations of clinical code usage of 1, 3 and 5 years. Three measures of diversity (Shannon entropy index of diversity, richness and evenness) were used to quantify changes in incident and total clinical codes.Results Overall, all examined conditions, except LD, showed positive monotonic correlation. HT, hypothyroidism, osteoarthritis and SMI codes’ usage had high 5-year correlation. The codes’ usage diversity remained stable overall throughout the study period. Cancer, diabetes and SMI had the highest richness (code lists need time to define) unlike AF, hypothyroidism and LD. SMI (high richness) and hypothyroidism (low richness) can last for 5 years, whereas cancer and diabetes (high richness) and LD (low richness) only last for 2 years.Conclusions This is an under-reported research area and the findings suggest the codes’ usage diversity for most conditions remained overall stable throughout the study period. Generated mental health code lists can last for a long time unlike cardiometabolic conditions and cancer. Adopting more consistent and less diverse coding would help improve data quality in primary care. Future research is needed following the transfer to the Systematised Nomenclature of Medicine Clinical Terms (SNOMED CT) coding.https://bmjopen.bmj.com/content/12/7/e051456.full
spellingShingle Christos Grigoroglou
Darren M Ashcroft
Evangelos Kontopantelis
David Reeves
Salwa S Zghebi
Rosa Parisi
Brian McMillan
Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years
BMJ Open
title Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years
title_full Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years
title_fullStr Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years
title_full_unstemmed Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years
title_short Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years
title_sort clinical code usage in uk general practice a cohort study exploring 18 conditions over 14 years
url https://bmjopen.bmj.com/content/12/7/e051456.full
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