Rapid and sustained antidepressant effects of tubastatin A in a mouse model of depression

Abstract Depression is a prevalent mental disorder and a leading risk factor for suicide. Conventional antidepressants, which target the monoaminergic system, often have delayed therapeutic effects and limited efficacy. Therefore, the development of faster-acting and more effective treatments is cri...

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Bibliographic Details
Main Authors: Masahide Fukada, Yoshiharu Kawaguchi, Atsuo Nakayama
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-89551-7
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