Differing Pattern of Ambulatory Blood Pressure in Very Elderly Men Expresses Dynamics in Atherosclerotic Load in the Senescence

To assess an impact of vascular risk factors on ambulatory blood pressure measurement (ABPM) in the elderly, we followed up a population-based cohort of men from 68 until 82 years, when 104 survivors underwent ABPM. Results. At age 68, hypertension and high clinic blood pressure (CBP) did not predic...

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Main Authors: Arkadiusz Siennicki-Lantz, Sölve Elmståhl
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2012/417291
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author Arkadiusz Siennicki-Lantz
Sölve Elmståhl
author_facet Arkadiusz Siennicki-Lantz
Sölve Elmståhl
author_sort Arkadiusz Siennicki-Lantz
collection DOAJ
description To assess an impact of vascular risk factors on ambulatory blood pressure measurement (ABPM) in the elderly, we followed up a population-based cohort of men from 68 until 82 years, when 104 survivors underwent ABPM. Results. At age 68, hypertension and high clinic blood pressure (CBP) did not predict ABPM level. Smoking and low ankle-brachial index (ABI) predicted higher ABPM variability and pulse pressure (PP), but not absolute ABPM values. At age 82, hypertension, high or increasing CBP, strongly positively correlated with all variables of ABPM. Carotid stenosis, low or declining ABI during followup, correlated with higher nocturnal ABPM and PP. Concluding. Hypertension and vascular risk factors in a cohort of 68-year-old men do not result in higher ABPM at age 82, possibly due to inflection point in their pressure development. Higher ABPM reflects instead an increasing CBP and aggravating atherosclerosis during the preceding decade in that part of the cohort with previously favorable risk factor status.
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spelling doaj-art-40988337a7df4356bee646f5c7f047202025-02-03T01:31:10ZengWileyInternational Journal of Hypertension2090-03842090-03922012-01-01201210.1155/2012/417291417291Differing Pattern of Ambulatory Blood Pressure in Very Elderly Men Expresses Dynamics in Atherosclerotic Load in the SenescenceArkadiusz Siennicki-Lantz0Sölve Elmståhl1Division of Geriatric Medicine, Department of Health Sciences, Skane University Hospital in Malmö, Lund University, SE-205 02 Malmö, SwedenDivision of Geriatric Medicine, Department of Health Sciences, Skane University Hospital in Malmö, Lund University, SE-205 02 Malmö, SwedenTo assess an impact of vascular risk factors on ambulatory blood pressure measurement (ABPM) in the elderly, we followed up a population-based cohort of men from 68 until 82 years, when 104 survivors underwent ABPM. Results. At age 68, hypertension and high clinic blood pressure (CBP) did not predict ABPM level. Smoking and low ankle-brachial index (ABI) predicted higher ABPM variability and pulse pressure (PP), but not absolute ABPM values. At age 82, hypertension, high or increasing CBP, strongly positively correlated with all variables of ABPM. Carotid stenosis, low or declining ABI during followup, correlated with higher nocturnal ABPM and PP. Concluding. Hypertension and vascular risk factors in a cohort of 68-year-old men do not result in higher ABPM at age 82, possibly due to inflection point in their pressure development. Higher ABPM reflects instead an increasing CBP and aggravating atherosclerosis during the preceding decade in that part of the cohort with previously favorable risk factor status.http://dx.doi.org/10.1155/2012/417291
spellingShingle Arkadiusz Siennicki-Lantz
Sölve Elmståhl
Differing Pattern of Ambulatory Blood Pressure in Very Elderly Men Expresses Dynamics in Atherosclerotic Load in the Senescence
International Journal of Hypertension
title Differing Pattern of Ambulatory Blood Pressure in Very Elderly Men Expresses Dynamics in Atherosclerotic Load in the Senescence
title_full Differing Pattern of Ambulatory Blood Pressure in Very Elderly Men Expresses Dynamics in Atherosclerotic Load in the Senescence
title_fullStr Differing Pattern of Ambulatory Blood Pressure in Very Elderly Men Expresses Dynamics in Atherosclerotic Load in the Senescence
title_full_unstemmed Differing Pattern of Ambulatory Blood Pressure in Very Elderly Men Expresses Dynamics in Atherosclerotic Load in the Senescence
title_short Differing Pattern of Ambulatory Blood Pressure in Very Elderly Men Expresses Dynamics in Atherosclerotic Load in the Senescence
title_sort differing pattern of ambulatory blood pressure in very elderly men expresses dynamics in atherosclerotic load in the senescence
url http://dx.doi.org/10.1155/2012/417291
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AT solveelmstahl differingpatternofambulatorybloodpressureinveryelderlymenexpressesdynamicsinatheroscleroticloadinthesenescence