Differential expression of plasma proteins and pathway enrichments in pediatric diabetic ketoacidosis

Differential expression of plasma proteins and pathway enrichments in pediatric diabetic ketoacidosis

Abstract Background In children with type 1 diabetes (T1D), diabetic ketoacidosis (DKA) triggers a significant inflammatory response; however, the specific effector proteins and signaling pathways involved remain largely unexplored. This pediatric case–control study utilized plasma proteomics to exp...

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Bibliographic Details
Main Authors: Paolo Spagnolo, Enis Cela, Maitray A. Patel, David Tweddell, Mark Daley, Cheril Clarson, Saverio Stranges, Gediminas Cepinskas, Douglas D. Fraser
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Medicine
Subjects:
Pediatric
Diabetic ketoacidosis
Proteomics
Protein expression
Pathways
Online Access:https://doi.org/10.1186/s10020-024-01056-7
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