Usefulness of Magnifying Endoscopy with Narrow-Band Imaging for Determining Tumor Invasion Depth in Early Gastric Cancer
Backgrounds. Magnifying endoscopy with narrow-band imaging (ME-NBI) has become essential for determining tumor margin in early gastric cancer (EGC). Here, we investigated the usefulness of ME-NBI for assessment of invasion depth in EGC. Methods. For 119 patients who had undergone ME-NBI and en bloc...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2013/217695 |
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| author | Daisuke Kikuchi Toshiro Iizuka Shu Hoteya Akihiro Yamada Tsukasa Furuhata Satoshi Yamashita Kaoru Domon Masanori Nakamura Akira Matsui Toshifumi Mitani Osamu Ogawa Sumio Watanabe Mitsuru Kaise |
| author_facet | Daisuke Kikuchi Toshiro Iizuka Shu Hoteya Akihiro Yamada Tsukasa Furuhata Satoshi Yamashita Kaoru Domon Masanori Nakamura Akira Matsui Toshifumi Mitani Osamu Ogawa Sumio Watanabe Mitsuru Kaise |
| author_sort | Daisuke Kikuchi |
| collection | DOAJ |
| description | Backgrounds. Magnifying endoscopy with narrow-band imaging (ME-NBI) has become essential for determining tumor margin in early gastric cancer (EGC). Here, we investigated the usefulness of ME-NBI for assessment of invasion depth in EGC.
Methods. For 119 patients who had undergone ME-NBI and en bloc resection by endoscopic submucosal dissection, three physicians prospectively examined high-magnification ME-NBI images for clinical features such as presence or absence of dilated vessels (D vessels). Cases with D vessels verified by at least two physicians were assigned to group V, and others were assigned to group N. We then compared clinicopathological factors associated with the groups. Results. Groups V and N consisted of 18 and 101 patients, respectively. There were no significant differences in age, gender, tumor size, tumor location, gross morphology, or histological type. The percentage of submucosal cancer was 9.9% (10/101) in group N and significantly higher at 33.3% (6/18) in group V (). When the presence of D vessels was considered a diagnostic criterion for submucosal cancer, diagnostic accuracy, sensitivity, and specificity were 81.5, 37.5, and 88.3%, respectively. Conclusions. The results suggest that identification of D vessels using ME-NBI can assist in the assessment of invasion depth in EGC. |
| format | Article |
| id | doaj-art-4085858340c342198b3ab0a74d964745 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-4085858340c342198b3ab0a74d9647452025-02-03T01:07:25ZengWileyGastroenterology Research and Practice1687-61211687-630X2013-01-01201310.1155/2013/217695217695Usefulness of Magnifying Endoscopy with Narrow-Band Imaging for Determining Tumor Invasion Depth in Early Gastric CancerDaisuke Kikuchi0Toshiro Iizuka1Shu Hoteya2Akihiro Yamada3Tsukasa Furuhata4Satoshi Yamashita5Kaoru Domon6Masanori Nakamura7Akira Matsui8Toshifumi Mitani9Osamu Ogawa10Sumio Watanabe11Mitsuru Kaise12Department of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanDepartment of Gastroenterology, Juntendo University, Tokyo 113-0033, JapanDepartment of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, JapanBackgrounds. Magnifying endoscopy with narrow-band imaging (ME-NBI) has become essential for determining tumor margin in early gastric cancer (EGC). Here, we investigated the usefulness of ME-NBI for assessment of invasion depth in EGC. Methods. For 119 patients who had undergone ME-NBI and en bloc resection by endoscopic submucosal dissection, three physicians prospectively examined high-magnification ME-NBI images for clinical features such as presence or absence of dilated vessels (D vessels). Cases with D vessels verified by at least two physicians were assigned to group V, and others were assigned to group N. We then compared clinicopathological factors associated with the groups. Results. Groups V and N consisted of 18 and 101 patients, respectively. There were no significant differences in age, gender, tumor size, tumor location, gross morphology, or histological type. The percentage of submucosal cancer was 9.9% (10/101) in group N and significantly higher at 33.3% (6/18) in group V (). When the presence of D vessels was considered a diagnostic criterion for submucosal cancer, diagnostic accuracy, sensitivity, and specificity were 81.5, 37.5, and 88.3%, respectively. Conclusions. The results suggest that identification of D vessels using ME-NBI can assist in the assessment of invasion depth in EGC.http://dx.doi.org/10.1155/2013/217695 |
| spellingShingle | Daisuke Kikuchi Toshiro Iizuka Shu Hoteya Akihiro Yamada Tsukasa Furuhata Satoshi Yamashita Kaoru Domon Masanori Nakamura Akira Matsui Toshifumi Mitani Osamu Ogawa Sumio Watanabe Mitsuru Kaise Usefulness of Magnifying Endoscopy with Narrow-Band Imaging for Determining Tumor Invasion Depth in Early Gastric Cancer Gastroenterology Research and Practice |
| title | Usefulness of Magnifying Endoscopy with Narrow-Band Imaging for Determining Tumor Invasion Depth in Early Gastric Cancer |
| title_full | Usefulness of Magnifying Endoscopy with Narrow-Band Imaging for Determining Tumor Invasion Depth in Early Gastric Cancer |
| title_fullStr | Usefulness of Magnifying Endoscopy with Narrow-Band Imaging for Determining Tumor Invasion Depth in Early Gastric Cancer |
| title_full_unstemmed | Usefulness of Magnifying Endoscopy with Narrow-Band Imaging for Determining Tumor Invasion Depth in Early Gastric Cancer |
| title_short | Usefulness of Magnifying Endoscopy with Narrow-Band Imaging for Determining Tumor Invasion Depth in Early Gastric Cancer |
| title_sort | usefulness of magnifying endoscopy with narrow band imaging for determining tumor invasion depth in early gastric cancer |
| url | http://dx.doi.org/10.1155/2013/217695 |
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