First episode of psychiatric and neuropsychiatric disease among patients infected with COVID‐19: A scoping review

Abstract This scoping review aims to examine the frequency and prevalence of neuropsychiatric disorders reported in patients infected with coronavirus disease 2019, and the mechanisms by which these develop during and post infection. A systematic search using relevant search terms and key words was...

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Main Authors: Wali Yousufzai, Alex Heo, Kyle Gu, Edward Sun, Gabriel Lopez, Shreya Balamurali, Jennifer Adjei‐Mosi, Riley Shin, Daniel B. Stuart, Peggy Edwards, Regina Baronia, Wail Amor, Terry McMahon
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:PCN Reports
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Online Access:https://doi.org/10.1002/pcn5.70146
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author Wali Yousufzai
Alex Heo
Kyle Gu
Edward Sun
Gabriel Lopez
Shreya Balamurali
Jennifer Adjei‐Mosi
Riley Shin
Daniel B. Stuart
Peggy Edwards
Regina Baronia
Wail Amor
Terry McMahon
author_facet Wali Yousufzai
Alex Heo
Kyle Gu
Edward Sun
Gabriel Lopez
Shreya Balamurali
Jennifer Adjei‐Mosi
Riley Shin
Daniel B. Stuart
Peggy Edwards
Regina Baronia
Wail Amor
Terry McMahon
author_sort Wali Yousufzai
collection DOAJ
description Abstract This scoping review aims to examine the frequency and prevalence of neuropsychiatric disorders reported in patients infected with coronavirus disease 2019, and the mechanisms by which these develop during and post infection. A systematic search using relevant search terms and key words was done on six electronic databases of literature on neuropsychiatric conditions post‐coronavirus disease 2019 infection from 2020 to 2023. Data were extracted following Joanna Briggs Institute guidelines, focusing on key findings, intervention details, and outcomes. We included 333 studies in the review. Studies indicated an elevated risk of neuropsychiatric disorders post‐coronavirus disease 2019, with some risks remaining high 2 years after diagnosis. A significant prevalence of depressive, psychotic, and anxiety disorders, as well as post‐traumatic stress symptoms were noted among coronavirus disease 2019 survivors. There was increased prevalence of insomnia and other sleep disturbances, mild to severe cognitive dysfunction, and eating disorders. Coronavirus disease 2019 infection is associated with a significant risk of developing various neuropsychiatric disorders, including schizophrenia, depressive disorders, anxiety, post‐traumatic stress disorder, and cognitive dysfunction. Long‐term monitoring and early interventions are essential to mitigate these risks and improve patient outcomes.
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spelling doaj-art-4083dc00a5c44bb4980b6e2e1b423e482025-08-20T03:27:10ZengWileyPCN Reports2769-25582025-06-0142n/an/a10.1002/pcn5.70146First episode of psychiatric and neuropsychiatric disease among patients infected with COVID‐19: A scoping reviewWali Yousufzai0Alex Heo1Kyle Gu2Edward Sun3Gabriel Lopez4Shreya Balamurali5Jennifer Adjei‐Mosi6Riley Shin7Daniel B. Stuart8Peggy Edwards9Regina Baronia10Wail Amor11Terry McMahon12Psychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USANassau University Medical Center East Meadow New York USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAPsychiatry Department Texas Tech University Health Sciences Lubbock Lubbock Texas USAAbstract This scoping review aims to examine the frequency and prevalence of neuropsychiatric disorders reported in patients infected with coronavirus disease 2019, and the mechanisms by which these develop during and post infection. A systematic search using relevant search terms and key words was done on six electronic databases of literature on neuropsychiatric conditions post‐coronavirus disease 2019 infection from 2020 to 2023. Data were extracted following Joanna Briggs Institute guidelines, focusing on key findings, intervention details, and outcomes. We included 333 studies in the review. Studies indicated an elevated risk of neuropsychiatric disorders post‐coronavirus disease 2019, with some risks remaining high 2 years after diagnosis. A significant prevalence of depressive, psychotic, and anxiety disorders, as well as post‐traumatic stress symptoms were noted among coronavirus disease 2019 survivors. There was increased prevalence of insomnia and other sleep disturbances, mild to severe cognitive dysfunction, and eating disorders. Coronavirus disease 2019 infection is associated with a significant risk of developing various neuropsychiatric disorders, including schizophrenia, depressive disorders, anxiety, post‐traumatic stress disorder, and cognitive dysfunction. Long‐term monitoring and early interventions are essential to mitigate these risks and improve patient outcomes.https://doi.org/10.1002/pcn5.70146COVID‐19depressionneurocognitive disorderneuropsychiatry
spellingShingle Wali Yousufzai
Alex Heo
Kyle Gu
Edward Sun
Gabriel Lopez
Shreya Balamurali
Jennifer Adjei‐Mosi
Riley Shin
Daniel B. Stuart
Peggy Edwards
Regina Baronia
Wail Amor
Terry McMahon
First episode of psychiatric and neuropsychiatric disease among patients infected with COVID‐19: A scoping review
PCN Reports
COVID‐19
depression
neurocognitive disorder
neuropsychiatry
title First episode of psychiatric and neuropsychiatric disease among patients infected with COVID‐19: A scoping review
title_full First episode of psychiatric and neuropsychiatric disease among patients infected with COVID‐19: A scoping review
title_fullStr First episode of psychiatric and neuropsychiatric disease among patients infected with COVID‐19: A scoping review
title_full_unstemmed First episode of psychiatric and neuropsychiatric disease among patients infected with COVID‐19: A scoping review
title_short First episode of psychiatric and neuropsychiatric disease among patients infected with COVID‐19: A scoping review
title_sort first episode of psychiatric and neuropsychiatric disease among patients infected with covid 19 a scoping review
topic COVID‐19
depression
neurocognitive disorder
neuropsychiatry
url https://doi.org/10.1002/pcn5.70146
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