Brain Symmetry Index in Healthy and Stroke Patients for Assessment and Prognosis
Objective. Quantitative neurophysiological signal parameters are of value in predicting motor recovery after stroke. The novel role of EEG-derived brain symmetry index for motor function prognostication in the subacute phase after stroke is explored. Methods. Ten male stroke patients and ten matched...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017-01-01
|
| Series: | Stroke Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2017/8276136 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832567364951998464 |
|---|---|
| author | Andrei Agius Anastasi Owen Falzon Kenneth Camilleri Malcolm Vella Richard Muscat |
| author_facet | Andrei Agius Anastasi Owen Falzon Kenneth Camilleri Malcolm Vella Richard Muscat |
| author_sort | Andrei Agius Anastasi |
| collection | DOAJ |
| description | Objective. Quantitative neurophysiological signal parameters are of value in predicting motor recovery after stroke. The novel role of EEG-derived brain symmetry index for motor function prognostication in the subacute phase after stroke is explored. Methods. Ten male stroke patients and ten matched healthy controls were recruited. Motor function was first assessed clinically using the MRC score, its derivative Motricity Index, and the Fugl–Meyer assessment score. EEG was subsequently recorded first with subjects at rest and then during hand grasping motions, triggered by visual cues. Brain symmetry index (BSI) was used to identify the differences in EEG-quantified interhemispheric cortical power asymmetry observable in healthy versus cortical and subcortical stroke patients. Subsequently, any correlation between BSI and motor function was explored. Results. BSI was found to be significantly higher in stroke subjects compared to healthy controls (p=0.023). The difference in BSI was more pronounced in the cortical stroke subgroup (p=0.016). BSI showed only a mild general decrease on repeated monthly recording. Notably, a statistically significant correlation was observed between early BSI and Fugl–Meyer score later in recovery (p<0.050). Conclusions. Brain symmetry index is increased in the subacute poststroke phase and correlates with motor function 1-2 months after stroke. |
| format | Article |
| id | doaj-art-4070a66d3f834316912e76dd6a2d3c05 |
| institution | Kabale University |
| issn | 2090-8105 2042-0056 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stroke Research and Treatment |
| spelling | doaj-art-4070a66d3f834316912e76dd6a2d3c052025-02-03T01:01:43ZengWileyStroke Research and Treatment2090-81052042-00562017-01-01201710.1155/2017/82761368276136Brain Symmetry Index in Healthy and Stroke Patients for Assessment and PrognosisAndrei Agius Anastasi0Owen Falzon1Kenneth Camilleri2Malcolm Vella3Richard Muscat4Department of Physiology & Biochemistry, Faculty of Medicine & Surgery, University of Malta, Msida, MaltaCentre for Biomedical Cybernetics, University of Malta, Msida, MaltaCentre for Biomedical Cybernetics, University of Malta, Msida, MaltaNeurology Department, Mater Dei Hospital, Msida, MaltaDepartment of Physiology & Biochemistry, Faculty of Medicine & Surgery, University of Malta, Msida, MaltaObjective. Quantitative neurophysiological signal parameters are of value in predicting motor recovery after stroke. The novel role of EEG-derived brain symmetry index for motor function prognostication in the subacute phase after stroke is explored. Methods. Ten male stroke patients and ten matched healthy controls were recruited. Motor function was first assessed clinically using the MRC score, its derivative Motricity Index, and the Fugl–Meyer assessment score. EEG was subsequently recorded first with subjects at rest and then during hand grasping motions, triggered by visual cues. Brain symmetry index (BSI) was used to identify the differences in EEG-quantified interhemispheric cortical power asymmetry observable in healthy versus cortical and subcortical stroke patients. Subsequently, any correlation between BSI and motor function was explored. Results. BSI was found to be significantly higher in stroke subjects compared to healthy controls (p=0.023). The difference in BSI was more pronounced in the cortical stroke subgroup (p=0.016). BSI showed only a mild general decrease on repeated monthly recording. Notably, a statistically significant correlation was observed between early BSI and Fugl–Meyer score later in recovery (p<0.050). Conclusions. Brain symmetry index is increased in the subacute poststroke phase and correlates with motor function 1-2 months after stroke.http://dx.doi.org/10.1155/2017/8276136 |
| spellingShingle | Andrei Agius Anastasi Owen Falzon Kenneth Camilleri Malcolm Vella Richard Muscat Brain Symmetry Index in Healthy and Stroke Patients for Assessment and Prognosis Stroke Research and Treatment |
| title | Brain Symmetry Index in Healthy and Stroke Patients for Assessment and Prognosis |
| title_full | Brain Symmetry Index in Healthy and Stroke Patients for Assessment and Prognosis |
| title_fullStr | Brain Symmetry Index in Healthy and Stroke Patients for Assessment and Prognosis |
| title_full_unstemmed | Brain Symmetry Index in Healthy and Stroke Patients for Assessment and Prognosis |
| title_short | Brain Symmetry Index in Healthy and Stroke Patients for Assessment and Prognosis |
| title_sort | brain symmetry index in healthy and stroke patients for assessment and prognosis |
| url | http://dx.doi.org/10.1155/2017/8276136 |
| work_keys_str_mv | AT andreiagiusanastasi brainsymmetryindexinhealthyandstrokepatientsforassessmentandprognosis AT owenfalzon brainsymmetryindexinhealthyandstrokepatientsforassessmentandprognosis AT kennethcamilleri brainsymmetryindexinhealthyandstrokepatientsforassessmentandprognosis AT malcolmvella brainsymmetryindexinhealthyandstrokepatientsforassessmentandprognosis AT richardmuscat brainsymmetryindexinhealthyandstrokepatientsforassessmentandprognosis |