Gastric and Duodenal Pseudomelanosis: An Extended Unusual Finding in a Patient with End Stage Kidney Disease
Gastric and duodenal pseudomelanosis is a rare endoscopic mucosal finding, characterized by the accumulation of iron in macrophages of the lamina propria of the stomach and duodenum. The clinical significance and long term sequelae have not been clarified yet. However, this benign condition is assoc...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/2861086 |
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| author | Noor Ul Ain Qureshi Muhammad Faraz Younus Kourosh Alavi Muhammad Yasin Sheikh |
| author_facet | Noor Ul Ain Qureshi Muhammad Faraz Younus Kourosh Alavi Muhammad Yasin Sheikh |
| author_sort | Noor Ul Ain Qureshi |
| collection | DOAJ |
| description | Gastric and duodenal pseudomelanosis is a rare endoscopic mucosal finding, characterized by the accumulation of iron in macrophages of the lamina propria of the stomach and duodenum. The clinical significance and long term sequelae have not been clarified yet. However, this benign condition is associated with a variety of clinical conditions, such as essential hypertension, chronic renal failure, diabetes mellitus, long term intake of iron supplements, and furosemide. Duodenal pseudomelanosis appears to be more common than gastric pseudomelanosis given the fact that a few cases of gastric pseudomelanosis have been reported in the literature so far. We report a case of 88-year-old lady with ESRD who is maintained on hemodialysis and presented with abdominal pain. An upper GI endoscopy showed discoloration of the antrum of the stomach and most portion of her duodenum. Histopathology report confirmed the presence of iron laden macrophages in the lamina propria of both stomach and duodenum. |
| format | Article |
| id | doaj-art-4065f8623cc44ff090fdd3bf18fe963b |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-4065f8623cc44ff090fdd3bf18fe963b2025-02-03T05:57:47ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362016-01-01201610.1155/2016/28610862861086Gastric and Duodenal Pseudomelanosis: An Extended Unusual Finding in a Patient with End Stage Kidney DiseaseNoor Ul Ain Qureshi0Muhammad Faraz Younus1Kourosh Alavi2Muhammad Yasin Sheikh3Division of Gastroenterology and Hepatology, University of California San Francisco (UCSF), 1st Floor, Endoscopy Suite, 2823 Fresno Street, Fresno, CA 93721, USAUniversity of Nevada, 1155 Mill Street, Reno, NV 89502, USADivision of Gastroenterology and Hepatology, University of California San Francisco (UCSF), 1st Floor, Endoscopy Suite, 2823 Fresno Street, Fresno, CA 93721, USADivision of Gastroenterology and Hepatology, University of California San Francisco (UCSF), 1st Floor, Endoscopy Suite, 2823 Fresno Street, Fresno, CA 93721, USAGastric and duodenal pseudomelanosis is a rare endoscopic mucosal finding, characterized by the accumulation of iron in macrophages of the lamina propria of the stomach and duodenum. The clinical significance and long term sequelae have not been clarified yet. However, this benign condition is associated with a variety of clinical conditions, such as essential hypertension, chronic renal failure, diabetes mellitus, long term intake of iron supplements, and furosemide. Duodenal pseudomelanosis appears to be more common than gastric pseudomelanosis given the fact that a few cases of gastric pseudomelanosis have been reported in the literature so far. We report a case of 88-year-old lady with ESRD who is maintained on hemodialysis and presented with abdominal pain. An upper GI endoscopy showed discoloration of the antrum of the stomach and most portion of her duodenum. Histopathology report confirmed the presence of iron laden macrophages in the lamina propria of both stomach and duodenum.http://dx.doi.org/10.1155/2016/2861086 |
| spellingShingle | Noor Ul Ain Qureshi Muhammad Faraz Younus Kourosh Alavi Muhammad Yasin Sheikh Gastric and Duodenal Pseudomelanosis: An Extended Unusual Finding in a Patient with End Stage Kidney Disease Case Reports in Gastrointestinal Medicine |
| title | Gastric and Duodenal Pseudomelanosis: An Extended Unusual Finding in a Patient with End Stage Kidney Disease |
| title_full | Gastric and Duodenal Pseudomelanosis: An Extended Unusual Finding in a Patient with End Stage Kidney Disease |
| title_fullStr | Gastric and Duodenal Pseudomelanosis: An Extended Unusual Finding in a Patient with End Stage Kidney Disease |
| title_full_unstemmed | Gastric and Duodenal Pseudomelanosis: An Extended Unusual Finding in a Patient with End Stage Kidney Disease |
| title_short | Gastric and Duodenal Pseudomelanosis: An Extended Unusual Finding in a Patient with End Stage Kidney Disease |
| title_sort | gastric and duodenal pseudomelanosis an extended unusual finding in a patient with end stage kidney disease |
| url | http://dx.doi.org/10.1155/2016/2861086 |
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