Possible Nonopioid-Mediated Analgesia Produced by Methotrimeprazine in Rats
BACKGROUND: Several reports in the 1960s demonstrated that methotrimeprazine (MTMZ), a phenothiazine derivative, is effective for treating acute and chronic pain. Although MTMZ has received little attention in recent decades, the fact that it derives from a class of drugs usually associated with cog...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1996-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/1996/631681 |
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| _version_ | 1832551456995016704 |
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| author | Perry N Fuchs Bradley Kerr Ronald Melzack |
| author_facet | Perry N Fuchs Bradley Kerr Ronald Melzack |
| author_sort | Perry N Fuchs |
| collection | DOAJ |
| description | BACKGROUND: Several reports in the 1960s demonstrated that methotrimeprazine (MTMZ), a phenothiazine derivative, is effective for treating acute and chronic pain. Although MTMZ has received little attention in recent decades, the fact that it derives from a class of drugs usually associated with cognitive and emotional processes, rather than the traditional analgesics, makes it interesting as a potential source of information about the mechanisms of analgesia. |
| format | Article |
| id | doaj-art-405a696588b140b0935f55be1f44dc51 |
| institution | Kabale University |
| issn | 1203-6765 |
| language | English |
| publishDate | 1996-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-405a696588b140b0935f55be1f44dc512025-02-03T06:01:27ZengWileyPain Research and Management1203-67651996-01-011420721110.1155/1996/631681Possible Nonopioid-Mediated Analgesia Produced by Methotrimeprazine in RatsPerry N FuchsBradley KerrRonald MelzackBACKGROUND: Several reports in the 1960s demonstrated that methotrimeprazine (MTMZ), a phenothiazine derivative, is effective for treating acute and chronic pain. Although MTMZ has received little attention in recent decades, the fact that it derives from a class of drugs usually associated with cognitive and emotional processes, rather than the traditional analgesics, makes it interesting as a potential source of information about the mechanisms of analgesia.http://dx.doi.org/10.1155/1996/631681 |
| spellingShingle | Perry N Fuchs Bradley Kerr Ronald Melzack Possible Nonopioid-Mediated Analgesia Produced by Methotrimeprazine in Rats Pain Research and Management |
| title | Possible Nonopioid-Mediated Analgesia Produced by Methotrimeprazine in Rats |
| title_full | Possible Nonopioid-Mediated Analgesia Produced by Methotrimeprazine in Rats |
| title_fullStr | Possible Nonopioid-Mediated Analgesia Produced by Methotrimeprazine in Rats |
| title_full_unstemmed | Possible Nonopioid-Mediated Analgesia Produced by Methotrimeprazine in Rats |
| title_short | Possible Nonopioid-Mediated Analgesia Produced by Methotrimeprazine in Rats |
| title_sort | possible nonopioid mediated analgesia produced by methotrimeprazine in rats |
| url | http://dx.doi.org/10.1155/1996/631681 |
| work_keys_str_mv | AT perrynfuchs possiblenonopioidmediatedanalgesiaproducedbymethotrimeprazineinrats AT bradleykerr possiblenonopioidmediatedanalgesiaproducedbymethotrimeprazineinrats AT ronaldmelzack possiblenonopioidmediatedanalgesiaproducedbymethotrimeprazineinrats |