Possible Nonopioid-Mediated Analgesia Produced by Methotrimeprazine in Rats
BACKGROUND: Several reports in the 1960s demonstrated that methotrimeprazine (MTMZ), a phenothiazine derivative, is effective for treating acute and chronic pain. Although MTMZ has received little attention in recent decades, the fact that it derives from a class of drugs usually associated with cog...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
1996-01-01
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Series: | Pain Research and Management |
Online Access: | http://dx.doi.org/10.1155/1996/631681 |
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Summary: | BACKGROUND: Several reports in the 1960s demonstrated that methotrimeprazine (MTMZ), a phenothiazine derivative, is effective for treating acute and chronic pain. Although MTMZ has received little attention in recent decades, the fact that it derives from a class of drugs usually associated with cognitive and emotional processes, rather than the traditional analgesics, makes it interesting as a potential source of information about the mechanisms of analgesia. |
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ISSN: | 1203-6765 |