Update on Myopia Risk Factors and Microenvironmental Changes

The focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. We review the current evidence for its complex genetics and evaluate the known or candidate genes and loc...

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Main Authors: Valeria Coviltir, Miruna Burcel, Alina Popa Cherecheanu, Catalina Ionescu, Dana Dascalescu, Vasile Potop, Marian Burcea
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2019/4960852
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author Valeria Coviltir
Miruna Burcel
Alina Popa Cherecheanu
Catalina Ionescu
Dana Dascalescu
Vasile Potop
Marian Burcea
author_facet Valeria Coviltir
Miruna Burcel
Alina Popa Cherecheanu
Catalina Ionescu
Dana Dascalescu
Vasile Potop
Marian Burcea
author_sort Valeria Coviltir
collection DOAJ
description The focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. We review the current evidence for its complex genetics and evaluate the known or candidate genes and loci. In addition, we discuss recent investigations regarding the role of environmental factors. This paper also covers current research aimed at elucidating the signaling pathways involved in the pathogenesis of myopia.
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institution Kabale University
issn 2090-004X
2090-0058
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Journal of Ophthalmology
spelling doaj-art-40586bae5ac048f99d28fcd6343900072025-02-03T01:02:20ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/49608524960852Update on Myopia Risk Factors and Microenvironmental ChangesValeria Coviltir0Miruna Burcel1Alina Popa Cherecheanu2Catalina Ionescu3Dana Dascalescu4Vasile Potop5Marian Burcea6Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bd. Eroii Sanitari 8, Bucharest, RomaniaOftaclinic Clinic, Bd. Marasesti 2B, Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bd. Eroii Sanitari 8, Bucharest, RomaniaCMDTAMP Clinic, Bucharest, RomaniaOftaclinic Clinic, Bd. Marasesti 2B, Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bd. Eroii Sanitari 8, Bucharest, RomaniaFaculty of Medicine, “Carol Davila” University of Medicine and Pharmacy, Bd. Eroii Sanitari 8, Bucharest, RomaniaThe focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. We review the current evidence for its complex genetics and evaluate the known or candidate genes and loci. In addition, we discuss recent investigations regarding the role of environmental factors. This paper also covers current research aimed at elucidating the signaling pathways involved in the pathogenesis of myopia.http://dx.doi.org/10.1155/2019/4960852
spellingShingle Valeria Coviltir
Miruna Burcel
Alina Popa Cherecheanu
Catalina Ionescu
Dana Dascalescu
Vasile Potop
Marian Burcea
Update on Myopia Risk Factors and Microenvironmental Changes
Journal of Ophthalmology
title Update on Myopia Risk Factors and Microenvironmental Changes
title_full Update on Myopia Risk Factors and Microenvironmental Changes
title_fullStr Update on Myopia Risk Factors and Microenvironmental Changes
title_full_unstemmed Update on Myopia Risk Factors and Microenvironmental Changes
title_short Update on Myopia Risk Factors and Microenvironmental Changes
title_sort update on myopia risk factors and microenvironmental changes
url http://dx.doi.org/10.1155/2019/4960852
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AT mirunaburcel updateonmyopiariskfactorsandmicroenvironmentalchanges
AT alinapopacherecheanu updateonmyopiariskfactorsandmicroenvironmentalchanges
AT catalinaionescu updateonmyopiariskfactorsandmicroenvironmentalchanges
AT danadascalescu updateonmyopiariskfactorsandmicroenvironmentalchanges
AT vasilepotop updateonmyopiariskfactorsandmicroenvironmentalchanges
AT marianburcea updateonmyopiariskfactorsandmicroenvironmentalchanges