Vaginal Primary Malignant Melanoma: A Rare and Aggressive Tumor
Vaginal primary malignant melanoma is a rare and very aggressive tumor. It most commonly occurs in postmenopausal women, with a mean age of 57 years. Our patient is an 80-year-old, postmenopausal Greek woman presented with a complaint of abnormal vaginal bleeding. On gynecologic examination there wa...
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Format: | Article |
Language: | English |
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Wiley
2013-01-01
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Series: | Case Reports in Obstetrics and Gynecology |
Online Access: | http://dx.doi.org/10.1155/2013/137908 |
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author | Georgios Androutsopoulos Emmanouil Terzakis Georgia Ioannidou Athanasios Tsamandas Georgios Decavalas |
author_facet | Georgios Androutsopoulos Emmanouil Terzakis Georgia Ioannidou Athanasios Tsamandas Georgios Decavalas |
author_sort | Georgios Androutsopoulos |
collection | DOAJ |
description | Vaginal primary malignant melanoma is a rare and very aggressive tumor. It most commonly occurs in postmenopausal women, with a mean age of 57 years. Our patient is an 80-year-old, postmenopausal Greek woman presented with a complaint of abnormal vaginal bleeding. On gynecologic examination there was a pigmented, raised, ulcerated, and irregular lesion cm in the upper third of anterior vaginal wall. She underwent a wide local excision of the lesion. The histopathology revealed vaginal primary malignant melanoma with ulceration and no clear surgical margins. She denied any additional surgical interventions and underwent to postoperative adjuvant radiotherapy. Follow up 5 months after initial diagnosis revealed no evidence of local recurrence or distant metastasis. The prognosis of vaginal primary malignant melanoma is very poor despite treatment modality, because most of the cases are diagnosed at advanced stage. Particularly patients with no clear surgical margins and tumor size >3 cm needed postoperative adjuvant radiotherapy. |
format | Article |
id | doaj-art-40534f6ff98148b19d57f253f57c2a74 |
institution | Kabale University |
issn | 2090-6684 2090-6692 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Obstetrics and Gynecology |
spelling | doaj-art-40534f6ff98148b19d57f253f57c2a742025-02-03T06:05:11ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922013-01-01201310.1155/2013/137908137908Vaginal Primary Malignant Melanoma: A Rare and Aggressive TumorGeorgios Androutsopoulos0Emmanouil Terzakis1Georgia Ioannidou2Athanasios Tsamandas3Georgios Decavalas4Department of Obstetrics and Gynaecology, University of Patras, Medical School, 26504 Rio, GreeceDepartment of Obstetrics and Gynaecology, University of Patras, Medical School, 26504 Rio, GreeceDepartment of Radiation Oncology, St. Savvas Anticancer-Oncologic Hospital, Athens, GreeceDepartment of Pathology, University of Patras, Medical School, 26504 Rio, GreeceDepartment of Obstetrics and Gynaecology, University of Patras, Medical School, 26504 Rio, GreeceVaginal primary malignant melanoma is a rare and very aggressive tumor. It most commonly occurs in postmenopausal women, with a mean age of 57 years. Our patient is an 80-year-old, postmenopausal Greek woman presented with a complaint of abnormal vaginal bleeding. On gynecologic examination there was a pigmented, raised, ulcerated, and irregular lesion cm in the upper third of anterior vaginal wall. She underwent a wide local excision of the lesion. The histopathology revealed vaginal primary malignant melanoma with ulceration and no clear surgical margins. She denied any additional surgical interventions and underwent to postoperative adjuvant radiotherapy. Follow up 5 months after initial diagnosis revealed no evidence of local recurrence or distant metastasis. The prognosis of vaginal primary malignant melanoma is very poor despite treatment modality, because most of the cases are diagnosed at advanced stage. Particularly patients with no clear surgical margins and tumor size >3 cm needed postoperative adjuvant radiotherapy.http://dx.doi.org/10.1155/2013/137908 |
spellingShingle | Georgios Androutsopoulos Emmanouil Terzakis Georgia Ioannidou Athanasios Tsamandas Georgios Decavalas Vaginal Primary Malignant Melanoma: A Rare and Aggressive Tumor Case Reports in Obstetrics and Gynecology |
title | Vaginal Primary Malignant Melanoma: A Rare and Aggressive Tumor |
title_full | Vaginal Primary Malignant Melanoma: A Rare and Aggressive Tumor |
title_fullStr | Vaginal Primary Malignant Melanoma: A Rare and Aggressive Tumor |
title_full_unstemmed | Vaginal Primary Malignant Melanoma: A Rare and Aggressive Tumor |
title_short | Vaginal Primary Malignant Melanoma: A Rare and Aggressive Tumor |
title_sort | vaginal primary malignant melanoma a rare and aggressive tumor |
url | http://dx.doi.org/10.1155/2013/137908 |
work_keys_str_mv | AT georgiosandroutsopoulos vaginalprimarymalignantmelanomaarareandaggressivetumor AT emmanouilterzakis vaginalprimarymalignantmelanomaarareandaggressivetumor AT georgiaioannidou vaginalprimarymalignantmelanomaarareandaggressivetumor AT athanasiostsamandas vaginalprimarymalignantmelanomaarareandaggressivetumor AT georgiosdecavalas vaginalprimarymalignantmelanomaarareandaggressivetumor |