Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome
The use of heparin and low-dose aspirin is the current conventional treatment for pregnant females with antiphospholipid syndrome (APS). However, there is no additional treatment recommended for cases where the standard treatment cannot prevent obstetric complications such as fetal loss and placenta...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2022/5612091 |
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| author | Yumika Takaki Atsushi Daimon Misa Nunode Tomohito Tanaka Daisuke Fujita Masahide Ohmichi |
| author_facet | Yumika Takaki Atsushi Daimon Misa Nunode Tomohito Tanaka Daisuke Fujita Masahide Ohmichi |
| author_sort | Yumika Takaki |
| collection | DOAJ |
| description | The use of heparin and low-dose aspirin is the current conventional treatment for pregnant females with antiphospholipid syndrome (APS). However, there is no additional treatment recommended for cases where the standard treatment cannot prevent obstetric complications such as fetal loss and placental insufficiency. Recently, the addition of a novel antimalarial, hydroxychloroquine (HCQ), to the conventional treatment has shown the potential to prevent obstetric complications. Herein, we report a case in which the addition of HCQ improved adverse pregnancy outcomes in a pregnant female with systemic lupus erythematosus and aspirin-heparin-resistant APS. |
| format | Article |
| id | doaj-art-404be9eaaa70487cb478db863e6dd067 |
| institution | Kabale University |
| issn | 2090-6692 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-404be9eaaa70487cb478db863e6dd0672025-02-03T06:11:51ZengWileyCase Reports in Obstetrics and Gynecology2090-66922022-01-01202210.1155/2022/5612091Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid SyndromeYumika Takaki0Atsushi Daimon1Misa Nunode2Tomohito Tanaka3Daisuke Fujita4Masahide Ohmichi5Department of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyDepartment of Obstetrics and GynecologyThe use of heparin and low-dose aspirin is the current conventional treatment for pregnant females with antiphospholipid syndrome (APS). However, there is no additional treatment recommended for cases where the standard treatment cannot prevent obstetric complications such as fetal loss and placental insufficiency. Recently, the addition of a novel antimalarial, hydroxychloroquine (HCQ), to the conventional treatment has shown the potential to prevent obstetric complications. Herein, we report a case in which the addition of HCQ improved adverse pregnancy outcomes in a pregnant female with systemic lupus erythematosus and aspirin-heparin-resistant APS.http://dx.doi.org/10.1155/2022/5612091 |
| spellingShingle | Yumika Takaki Atsushi Daimon Misa Nunode Tomohito Tanaka Daisuke Fujita Masahide Ohmichi Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome Case Reports in Obstetrics and Gynecology |
| title | Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
| title_full | Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
| title_fullStr | Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
| title_full_unstemmed | Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
| title_short | Efficacy of Hydroxychloroquine for Improving Pregnancy Outcomes in a Female with Systemic Lupus Erythematosus and Antiphospholipid Syndrome |
| title_sort | efficacy of hydroxychloroquine for improving pregnancy outcomes in a female with systemic lupus erythematosus and antiphospholipid syndrome |
| url | http://dx.doi.org/10.1155/2022/5612091 |
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