Non-acid reflux and sleep apnea: the importance of drug induced sleep endoscopy
Abstract Background We present the first case of a patient with obstructive sleep apnea syndrome (OSA), where drug induced sleep endoscopy was helpful to suspect a non-acid reflux disease and showed an improvement in a swollen epiglottis after treatment. Patient ameliorated significantly his disease...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2021-06-01
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| Series: | Journal of Otolaryngology - Head and Neck Surgery |
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| Online Access: | https://doi.org/10.1186/s40463-021-00526-w |
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| author | Carlos O’Connor-Reina Jose Maria Ignacio Garcia Peter Baptista Maria Teresa Garcia-Iriarte Carlos Casado Alba Monica Perona Paz Francisca Borrmann Laura Rodriguez Alcala Guillermo Plaza |
| author_facet | Carlos O’Connor-Reina Jose Maria Ignacio Garcia Peter Baptista Maria Teresa Garcia-Iriarte Carlos Casado Alba Monica Perona Paz Francisca Borrmann Laura Rodriguez Alcala Guillermo Plaza |
| author_sort | Carlos O’Connor-Reina |
| collection | DOAJ |
| description | Abstract Background We present the first case of a patient with obstructive sleep apnea syndrome (OSA), where drug induced sleep endoscopy was helpful to suspect a non-acid reflux disease and showed an improvement in a swollen epiglottis after treatment. Patient ameliorated significantly his disease only with medical therapy. Case presentation A 54-year-old man without significant anatomical findings with obstructive sleep apnea syndrome and non-acid gastroesophageal reflux disease (GERD) disease whose Apnea- hypopnea index (AHI) was significantly reduced with the intake of 500 mg of sodium alginate twice a day for 6 months. Conventional digestive tests such as esophagoscopy and simple- and double-channel 24-h pH-metry suggested mild GERD. Conventional proton-pump inhibitor treatment with pantoprazole (40 mg daily) was started without any improvement in his sleep. Multichannel intraluminal 24-h impedanciometry indicated the presence of severe pathological GER of gaseous origin. The patient’s AHI decreased from 25.3 at baseline to 8 after treatment with sodium alginate. A drug-induced sleep endoscopy study showed the changes before and after this treatment and was helpful for the diagnosis. Conclusions Thus, medical treatment can be a therapeutic option in some patients with OSA. Multichannel 24-h impedanciometry should be performed when nonacid GERD is suspected. |
| format | Article |
| id | doaj-art-40469499ce27419aa5e3598e1d5ffca0 |
| institution | Kabale University |
| issn | 1916-0216 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Otolaryngology - Head and Neck Surgery |
| spelling | doaj-art-40469499ce27419aa5e3598e1d5ffca02025-02-03T10:54:10ZengSAGE PublishingJournal of Otolaryngology - Head and Neck Surgery1916-02162021-06-015011510.1186/s40463-021-00526-wNon-acid reflux and sleep apnea: the importance of drug induced sleep endoscopyCarlos O’Connor-Reina0Jose Maria Ignacio Garcia1Peter Baptista2Maria Teresa Garcia-Iriarte3Carlos Casado Alba4Monica Perona5Paz Francisca Borrmann6Laura Rodriguez Alcala7Guillermo Plaza8Otorhinolaryngology Department, Hospital Quiron Salud MarbellaPulmonology Department, Hospital Quiron Salud MarbellaOtorhinolaryngology Department, Clinica Universitaria de NavarraOtorhinolaryngology Department, Hospital Universitario de ValmeClinica Universitaria de Navarra, School of MedicineDigestive Department, Hospital Quironsalud MarbellaPhonoaudiology Unit. Otorhinolaryngology Department Hospital Universitario Italiano Buenos AiresOtorhinolaryngology Department, Hospital Quiron Salud MarbellaOtorhinolaryngology Department, Hospital Universitario de Fuenlabrada & Hospital Sanitas la Zarzuela. Universidad Rey Juan CarlosAbstract Background We present the first case of a patient with obstructive sleep apnea syndrome (OSA), where drug induced sleep endoscopy was helpful to suspect a non-acid reflux disease and showed an improvement in a swollen epiglottis after treatment. Patient ameliorated significantly his disease only with medical therapy. Case presentation A 54-year-old man without significant anatomical findings with obstructive sleep apnea syndrome and non-acid gastroesophageal reflux disease (GERD) disease whose Apnea- hypopnea index (AHI) was significantly reduced with the intake of 500 mg of sodium alginate twice a day for 6 months. Conventional digestive tests such as esophagoscopy and simple- and double-channel 24-h pH-metry suggested mild GERD. Conventional proton-pump inhibitor treatment with pantoprazole (40 mg daily) was started without any improvement in his sleep. Multichannel intraluminal 24-h impedanciometry indicated the presence of severe pathological GER of gaseous origin. The patient’s AHI decreased from 25.3 at baseline to 8 after treatment with sodium alginate. A drug-induced sleep endoscopy study showed the changes before and after this treatment and was helpful for the diagnosis. Conclusions Thus, medical treatment can be a therapeutic option in some patients with OSA. Multichannel 24-h impedanciometry should be performed when nonacid GERD is suspected.https://doi.org/10.1186/s40463-021-00526-wObstructive sleep apneaNonacid reflux diseaseMultichannel impedanciometryEpiglottisContinuous positive airway pressureDrug-induced sleep endoscopy |
| spellingShingle | Carlos O’Connor-Reina Jose Maria Ignacio Garcia Peter Baptista Maria Teresa Garcia-Iriarte Carlos Casado Alba Monica Perona Paz Francisca Borrmann Laura Rodriguez Alcala Guillermo Plaza Non-acid reflux and sleep apnea: the importance of drug induced sleep endoscopy Journal of Otolaryngology - Head and Neck Surgery Obstructive sleep apnea Nonacid reflux disease Multichannel impedanciometry Epiglottis Continuous positive airway pressure Drug-induced sleep endoscopy |
| title | Non-acid reflux and sleep apnea: the importance of drug induced sleep endoscopy |
| title_full | Non-acid reflux and sleep apnea: the importance of drug induced sleep endoscopy |
| title_fullStr | Non-acid reflux and sleep apnea: the importance of drug induced sleep endoscopy |
| title_full_unstemmed | Non-acid reflux and sleep apnea: the importance of drug induced sleep endoscopy |
| title_short | Non-acid reflux and sleep apnea: the importance of drug induced sleep endoscopy |
| title_sort | non acid reflux and sleep apnea the importance of drug induced sleep endoscopy |
| topic | Obstructive sleep apnea Nonacid reflux disease Multichannel impedanciometry Epiglottis Continuous positive airway pressure Drug-induced sleep endoscopy |
| url | https://doi.org/10.1186/s40463-021-00526-w |
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