Switch of phosphorylation to O-GlcNAcylation of AhR contributes to vascular oxidative stress induced by benzo[a]pyrene

Switch of phosphorylation to O-GlcNAcylation of AhR contributes to vascular oxidative stress induced by benzo[a]pyrene

Benzo[a]pyrene (B[a]P) is a food contaminant toxic for cardiovascular diseases. The nuclear translocation of Arylhydrocarbon receptor (AhR) plays an important role in B[a]P-induced oxidative stress and vascular diseases. We confirmed that B[a]P promoted ROS production in vascular smooth muscle cells...

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Bibliographic Details
Main Authors: Rong Wang, Yun Huang, Xiaoruo Gan, Chenghao Fu, Yuemin Li, Ning Chen, Hao Xi, Huishan Guo, Wei Zhang, Yuhong Lü, Yan Zhang, Pin Lü
Format: Article
Language:English
Published: Tsinghua University Press 2023-11-01
Series:Food Science and Human Wellness
Subjects:
Benzo[a]pyrene
Vascular smooth muscle cells
Aryl hydrocarbon receptor
Phosphorylation modification
O-GlcNAcylation modification
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453023000988
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