CD93 blockade promotes effector T-cell infiltration and facilitates adoptive cell therapy in solid tumors
Background Adaptive cellular therapy (ACT), particularly chimeric antigen receptor (CAR)-T cell therapy, has been successful in the treatment of hemopoietic malignancies. However, poor trafficking of administered effector T cells to the tumor poses a great hurdle for this otherwise powerful therapeu...
Saved in:
| Main Authors: | Yi Sun, Eduardo Davila, YuJie Guo, Richard D Schulick, Elliott Yee, Yuki Fujiwara, Kaitlyn Dickinson, Zhiwei Sun, Junyi Hu, Yuwen Zhu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2025-01-01
|
| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/13/1/e010554.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Dendritic cell effector mechanisms and tumor immune microenvironment infiltration define TLR8 modulation and PD-1 blockade
by: Daniel A. Ruiz-Torres, et al.
Published: (2024-12-01) -
Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy
by: Xia Liu, et al.
Published: (2022-10-01) -
Targeting CD93 on monocytes revitalizes antitumor immunity by enhancing the function and infiltration of CD8+ T cells
by: Yan Wu, et al.
Published: (2024-10-01) -
Correction: Targeting CD93 on monocytes revitalizes antitumor immunity by enhancing the function and infiltration of CD8+ T cells
Published: (2024-11-01) -
Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade
by: Tullia C. Bruno, et al.
Published: (2025-08-01)