Autophagy-associated signal pathways of functional foods for chronic diseases
Functional foods, namely as natural or processed foods containing bioactive compounds, can provide health-promoting effects beyond basic nutrition, or offer the prevention or supplementary treatment of chronic diseases. The bioactive components in functional foods usually have pleiotropic effects, i...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2019-03-01
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| Series: | Food Science and Human Wellness |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453019300205 |
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| author | Jinfeng Xie Jiling Liang Ning Chen |
| author_facet | Jinfeng Xie Jiling Liang Ning Chen |
| author_sort | Jinfeng Xie |
| collection | DOAJ |
| description | Functional foods, namely as natural or processed foods containing bioactive compounds, can provide health-promoting effects beyond basic nutrition, or offer the prevention or supplementary treatment of chronic diseases. The bioactive components in functional foods usually have pleiotropic effects, including antioxidant, anti-inflammatory, hypolipidemic, glycemic-regulating, cytoprotective, and neuroprotective functions. Autophagy is one of the highly conserved cellular processes for the clearance of aberrant components in eukaryotic cells, and plays an essential role in health promotion and prevention and treatment of a series of chronic diseases. Once the cells are in the stress environment, the induced autophagy will accelerate the clearance of cellular damaged or toxic protein aggregates or dysfunctional cellular organelles to maintain homeostasis in cells. In this article, we summarize several widely investigated bioactive components used as functional foods, such as resveratrol, epigallocatechin-3-gallate, curcumin and trehalose, with the regulatory function for autophagy during the intervention of chronic diseases, which will provide the references or novel thoughts for the development of functional foods with the modulation of autophagy. Keywords: Autophagy, Chronic diseases, Resveratrol, Epigallocatechin-3-gallate, Curcumin, Trehalose |
| format | Article |
| id | doaj-art-401dc37ace244d6a9d8f353aa42ea471 |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2019-03-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-401dc37ace244d6a9d8f353aa42ea4712025-02-02T23:24:42ZengTsinghua University PressFood Science and Human Wellness2213-45302019-03-01812533Autophagy-associated signal pathways of functional foods for chronic diseasesJinfeng Xie0Jiling Liang1Ning Chen2Graduate School, Wuhan Sports University, Wuhan 430079, ChinaGraduate School, Wuhan Sports University, Wuhan 430079, ChinaTianjiu Research and Development Center for Exercise Nutrition and Foods, Hubei Key Laboratory of Exercise Training and Monitoring, College of Health Science, Wuhan Sports University, Wuhan 430079, China; Corresponding author.Functional foods, namely as natural or processed foods containing bioactive compounds, can provide health-promoting effects beyond basic nutrition, or offer the prevention or supplementary treatment of chronic diseases. The bioactive components in functional foods usually have pleiotropic effects, including antioxidant, anti-inflammatory, hypolipidemic, glycemic-regulating, cytoprotective, and neuroprotective functions. Autophagy is one of the highly conserved cellular processes for the clearance of aberrant components in eukaryotic cells, and plays an essential role in health promotion and prevention and treatment of a series of chronic diseases. Once the cells are in the stress environment, the induced autophagy will accelerate the clearance of cellular damaged or toxic protein aggregates or dysfunctional cellular organelles to maintain homeostasis in cells. In this article, we summarize several widely investigated bioactive components used as functional foods, such as resveratrol, epigallocatechin-3-gallate, curcumin and trehalose, with the regulatory function for autophagy during the intervention of chronic diseases, which will provide the references or novel thoughts for the development of functional foods with the modulation of autophagy. Keywords: Autophagy, Chronic diseases, Resveratrol, Epigallocatechin-3-gallate, Curcumin, Trehalosehttp://www.sciencedirect.com/science/article/pii/S2213453019300205 |
| spellingShingle | Jinfeng Xie Jiling Liang Ning Chen Autophagy-associated signal pathways of functional foods for chronic diseases Food Science and Human Wellness |
| title | Autophagy-associated signal pathways of functional foods for chronic diseases |
| title_full | Autophagy-associated signal pathways of functional foods for chronic diseases |
| title_fullStr | Autophagy-associated signal pathways of functional foods for chronic diseases |
| title_full_unstemmed | Autophagy-associated signal pathways of functional foods for chronic diseases |
| title_short | Autophagy-associated signal pathways of functional foods for chronic diseases |
| title_sort | autophagy associated signal pathways of functional foods for chronic diseases |
| url | http://www.sciencedirect.com/science/article/pii/S2213453019300205 |
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