High and Low Adherence to Mediterranean and DASH Diet Patterns and the Risk of Heart Failure: A Meta-Analysis of Observational Studies

Background. The relationship between heart failure (HF) and Mediterranean and DASH diets is not well delineated. This meta-analysis aimed to assess the effectiveness of high adherence to Mediterranean and DASH diets compared to low adherence in reducing the risk of incident HF (primary prevention of...

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Main Authors: Mehmet Emin Arayici, Mustafa Eray Kilic, Mehmet Birhan Yilmaz
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Life
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Online Access:https://www.mdpi.com/2075-1729/15/1/63
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author Mehmet Emin Arayici
Mustafa Eray Kilic
Mehmet Birhan Yilmaz
author_facet Mehmet Emin Arayici
Mustafa Eray Kilic
Mehmet Birhan Yilmaz
author_sort Mehmet Emin Arayici
collection DOAJ
description Background. The relationship between heart failure (HF) and Mediterranean and DASH diets is not well delineated. This meta-analysis aimed to assess the effectiveness of high adherence to Mediterranean and DASH diets compared to low adherence in reducing the risk of incident HF (primary prevention of HF) and reducing all-cause mortality in patients with HF (secondary prevention of HF). Methods. The reporting stages of this meta-analysis closely adhered to the PRISMA guidelines. A comprehensive literature search was undertaken for published papers in PubMed, Embase, EBSCO, ICTRP, and the NIH clinical trials databases. Results. A total of 16 reports from 14 studies were included in this paper. A significant inverse association was identified between high adherence to the Mediterranean diet model (compared to low adherence) and the risk of incident HF (OR = 0.77, 95% CI: 0.63–0.93, <i>p</i> = 0.007) among patients without previous diagnosis of HF. Similarly, there was a significant and inverse relationship between high adherence to the DASH diet (compared to low adherence) and the risk of incident HF (OR = 0.83, 95% CI: 0.70–0.98, <i>p</i> = 0.03) among patients without previous diagnosis of HF. High adherence to the Mediterranean diet model (compared to low adherence) was associated with lower all-cause mortality (OR = 0.88, 95% CI: 0.78–0.99, <i>p</i> = 0.03) among patients with HF. Conclusions. This paper demonstrated that high adherence to Mediterranean and DASH diets significantly reduced the risk of incident HF among individuals without a previous diagnosis of HF, whereas only high adherence to the Mediterranean diet was associated with lower all-cause mortality among patients with HF.
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spelling doaj-art-400601e275484c37b1e577318bb640e42025-01-24T13:38:38ZengMDPI AGLife2075-17292025-01-011516310.3390/life15010063High and Low Adherence to Mediterranean and DASH Diet Patterns and the Risk of Heart Failure: A Meta-Analysis of Observational StudiesMehmet Emin Arayici0Mustafa Eray Kilic1Mehmet Birhan Yilmaz2Department of Biostatistics and Medical Informatics, Faculty of Medicine, Dokuz Eylül University, 35340 İzmir, TürkiyeDepartment of Cardiology, Faculty of Medicine, Dokuz Eylül University, 35340 İzmir, TürkiyeDepartment of Cardiology, Faculty of Medicine, Dokuz Eylül University, 35340 İzmir, TürkiyeBackground. The relationship between heart failure (HF) and Mediterranean and DASH diets is not well delineated. This meta-analysis aimed to assess the effectiveness of high adherence to Mediterranean and DASH diets compared to low adherence in reducing the risk of incident HF (primary prevention of HF) and reducing all-cause mortality in patients with HF (secondary prevention of HF). Methods. The reporting stages of this meta-analysis closely adhered to the PRISMA guidelines. A comprehensive literature search was undertaken for published papers in PubMed, Embase, EBSCO, ICTRP, and the NIH clinical trials databases. Results. A total of 16 reports from 14 studies were included in this paper. A significant inverse association was identified between high adherence to the Mediterranean diet model (compared to low adherence) and the risk of incident HF (OR = 0.77, 95% CI: 0.63–0.93, <i>p</i> = 0.007) among patients without previous diagnosis of HF. Similarly, there was a significant and inverse relationship between high adherence to the DASH diet (compared to low adherence) and the risk of incident HF (OR = 0.83, 95% CI: 0.70–0.98, <i>p</i> = 0.03) among patients without previous diagnosis of HF. High adherence to the Mediterranean diet model (compared to low adherence) was associated with lower all-cause mortality (OR = 0.88, 95% CI: 0.78–0.99, <i>p</i> = 0.03) among patients with HF. Conclusions. This paper demonstrated that high adherence to Mediterranean and DASH diets significantly reduced the risk of incident HF among individuals without a previous diagnosis of HF, whereas only high adherence to the Mediterranean diet was associated with lower all-cause mortality among patients with HF.https://www.mdpi.com/2075-1729/15/1/63heart failureMediterranean dietDASH dietmeta-analysis
spellingShingle Mehmet Emin Arayici
Mustafa Eray Kilic
Mehmet Birhan Yilmaz
High and Low Adherence to Mediterranean and DASH Diet Patterns and the Risk of Heart Failure: A Meta-Analysis of Observational Studies
Life
heart failure
Mediterranean diet
DASH diet
meta-analysis
title High and Low Adherence to Mediterranean and DASH Diet Patterns and the Risk of Heart Failure: A Meta-Analysis of Observational Studies
title_full High and Low Adherence to Mediterranean and DASH Diet Patterns and the Risk of Heart Failure: A Meta-Analysis of Observational Studies
title_fullStr High and Low Adherence to Mediterranean and DASH Diet Patterns and the Risk of Heart Failure: A Meta-Analysis of Observational Studies
title_full_unstemmed High and Low Adherence to Mediterranean and DASH Diet Patterns and the Risk of Heart Failure: A Meta-Analysis of Observational Studies
title_short High and Low Adherence to Mediterranean and DASH Diet Patterns and the Risk of Heart Failure: A Meta-Analysis of Observational Studies
title_sort high and low adherence to mediterranean and dash diet patterns and the risk of heart failure a meta analysis of observational studies
topic heart failure
Mediterranean diet
DASH diet
meta-analysis
url https://www.mdpi.com/2075-1729/15/1/63
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