Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm
These days, the ability to predict the result of the development of the system is the guarantee of the successful functioning of the system. Improving the quality and volume of information, complicating its presentation, the need to detect hidden connections makes it ineffective, and most often impo...
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| Format: | Article |
| Language: | English |
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Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2023-01-01
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| Series: | Вавиловский журнал генетики и селекции |
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| Online Access: | https://vavilov.elpub.ru/jour/article/view/3578 |
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| author | M. O. Zelenskih A. E. Saprygin S. S. Tamozhnikov P. D. Rudych D. A. Lebedkin A. N. Savostyanov |
| author_facet | M. O. Zelenskih A. E. Saprygin S. S. Tamozhnikov P. D. Rudych D. A. Lebedkin A. N. Savostyanov |
| author_sort | M. O. Zelenskih |
| collection | DOAJ |
| description | These days, the ability to predict the result of the development of the system is the guarantee of the successful functioning of the system. Improving the quality and volume of information, complicating its presentation, the need to detect hidden connections makes it ineffective, and most often impossible, to use classical statistical forecasting methods. Among the various forecasting methods, methods based on the use of artificial neural networks occupy a special place. The main objective of our work is to create a neural network that predicts the risk of depression in a person using data obtained using a motor control performance testing system. The stop-signal paradigm (SSP) is an experimental technique to assess a person’s ability to activate deliberate movements or inhibit movements that have become inadequate to external conditions. In modern medicine, the SSP is most commonly used to diagnose movement disorders such as Parkinson’s disease or the effects of stroke. We hypothesized that SSP could serve as a basis for detecting the risk of affective diseases, including depression. The neural network we are developing is supposed to combine such behavioral indicators as: the amount of missed responses, amount of correct responses, average time, the amount of correct inhibition of movements after stopsignal onset. Such a combination of indicators will provide increased accuracy in predicting the presence of depression in a person. The artificial neural network implemented in the work allows diagnosing the risk of depression on the basis of the data obtained in the stop-signal task. An architecture was developed and a system was implemented for testing motor control indicators in humans, then it was tested in real experiments. A comparison of neural network technologies and methods of mathematical statistics was carried out. A neural network was implemented to diagnose the risk of depression using stop-signal paradigm data. The efficiency of the neural network (in terms of accuracy) was demonstrated on data with an expert assessment for the presence of depression and data from the motor control testing system. |
| format | Article |
| id | doaj-art-3febbc6014f840cfad67e4cc2fc84cbd |
| institution | Kabale University |
| issn | 2500-3259 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders |
| record_format | Article |
| series | Вавиловский журнал генетики и селекции |
| spelling | doaj-art-3febbc6014f840cfad67e4cc2fc84cbd2025-02-01T09:58:11ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592023-01-0126877377910.18699/VJGB-22-931315Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigmM. O. Zelenskih0A. E. Saprygin1S. S. Tamozhnikov2P. D. Rudych3D. A. Lebedkin4A. N. Savostyanov5Novosibirsk State UniversityInstitute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences; Scientific Research Institute of Neurosciences and MedicineScientific Research Institute of Neurosciences and MedicineNovosibirsk State University; Scientific Research Institute of Neurosciences and Medicine; Federal Research Center of Fundamental and Translational MedicineNovosibirsk State University; Federal Research Center of Fundamental and Translational MedicineNovosibirsk State University; Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences; Scientific Research Institute of Neurosciences and Medicine; Federal Research Center of Fundamental and Translational MedicineThese days, the ability to predict the result of the development of the system is the guarantee of the successful functioning of the system. Improving the quality and volume of information, complicating its presentation, the need to detect hidden connections makes it ineffective, and most often impossible, to use classical statistical forecasting methods. Among the various forecasting methods, methods based on the use of artificial neural networks occupy a special place. The main objective of our work is to create a neural network that predicts the risk of depression in a person using data obtained using a motor control performance testing system. The stop-signal paradigm (SSP) is an experimental technique to assess a person’s ability to activate deliberate movements or inhibit movements that have become inadequate to external conditions. In modern medicine, the SSP is most commonly used to diagnose movement disorders such as Parkinson’s disease or the effects of stroke. We hypothesized that SSP could serve as a basis for detecting the risk of affective diseases, including depression. The neural network we are developing is supposed to combine such behavioral indicators as: the amount of missed responses, amount of correct responses, average time, the amount of correct inhibition of movements after stopsignal onset. Such a combination of indicators will provide increased accuracy in predicting the presence of depression in a person. The artificial neural network implemented in the work allows diagnosing the risk of depression on the basis of the data obtained in the stop-signal task. An architecture was developed and a system was implemented for testing motor control indicators in humans, then it was tested in real experiments. A comparison of neural network technologies and methods of mathematical statistics was carried out. A neural network was implemented to diagnose the risk of depression using stop-signal paradigm data. The efficiency of the neural network (in terms of accuracy) was demonstrated on data with an expert assessment for the presence of depression and data from the motor control testing system.https://vavilov.elpub.ru/jour/article/view/3578stop signal paradigmartificial neural networksystem for depression risk assessmentmachine learning |
| spellingShingle | M. O. Zelenskih A. E. Saprygin S. S. Tamozhnikov P. D. Rudych D. A. Lebedkin A. N. Savostyanov Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm Вавиловский журнал генетики и селекции stop signal paradigm artificial neural network system for depression risk assessment machine learning |
| title | Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm |
| title_full | Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm |
| title_fullStr | Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm |
| title_full_unstemmed | Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm |
| title_short | Development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm |
| title_sort | development of a neural network for diagnosing the risk of depression according to the experimental data of the stop signal paradigm |
| topic | stop signal paradigm artificial neural network system for depression risk assessment machine learning |
| url | https://vavilov.elpub.ru/jour/article/view/3578 |
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