The Rise of CRISPR/Cas for Genome Editing in Stem Cells

Genetic manipulation is a powerful tool to establish the causal relationship between a genetic lesion and a particular pathological phenotype. The rise of CRISPR/Cas9 genome-engineering tools overcame the traditional technical bottleneck for routine site-specific genetic manipulation in cells. To cr...

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Bibliographic Details
Main Authors: Bing Shui, Liz Hernandez Matias, Yi Guo, Ying Peng
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2016/8140168
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