2-O-β-D-Glucopyranosyl-L-ascorbic acid, an ascorbic acid derivative isolated from the fruits of Lycium barbarum L., ameliorates high fructose-induced neuroinflammation in mice: involvement of gut microbiota and leaky gut

2-O-β-D-Glucopyranosyl-L-ascorbic acid, an ascorbic acid derivative isolated from the fruits of Lycium barbarum L., ameliorates high fructose-induced neuroinflammation in mice: involvement of gut microbiota and leaky gut

Western diet (rich in highly refined sugar and fat) can induce a range of metabolic dysfunctions in animals and humans, including neuroinflammation and cognitive function decline. Neuroinflammation and cognitive impairment, two critical pathological characteristics of Alzheimer’s disease, have been...

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Bibliographic Details
Main Authors: Wei Dong, Yujia Peng, Guijie Chen, Zhiyong Xie, Weiqi Xu, Wangting Zhou, Jia Mi, Lu Lu, Yi Sun, Xiaoxiong Zeng, Youlong Cao, Yamei Yan
Format: Article
Language:English
Published: Tsinghua University Press 2024-01-01
Series:Food Science and Human Wellness
Subjects:
Neuroinflammation
Gut microbiota
Leaky gut
Lipopolysaccharide
Fecal microbiome transplantation
2-O-β-D-Glucopyranosyl-L-ascorbic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453023001155
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