Effect of Oral PUVAsol on the Quality of Life in Indian Patients Having Chronic Plaque Psoriasis
Background. Psoriasis is associated with a high impact on health-related QoL (quality of life). PUVAsol has been successfully used for treating psoriasis instead of standard PUVA therapy in developing countries. However, data for PUVAsol therapy and its effect on QoL in psoriatic patients is meagre....
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | Dermatology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2014/291586 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832549371567144960 |
|---|---|
| author | Pratik Gahalaut Nitin Mishra Puneet S. Soodan Madhur K. Rastogi |
| author_facet | Pratik Gahalaut Nitin Mishra Puneet S. Soodan Madhur K. Rastogi |
| author_sort | Pratik Gahalaut |
| collection | DOAJ |
| description | Background. Psoriasis is associated with a high impact on health-related QoL (quality of life). PUVAsol has been successfully used for treating psoriasis instead of standard PUVA therapy in developing countries. However, data for PUVAsol therapy and its effect on QoL in psoriatic patients is meagre. Objective. To investigate the effect of PUVAsol on the quality of life in patients having chronic plaque psoriasis. Materials and Methods. An observational prospective study done in patients having chronic plaque psoriasis. PASI and DLQI were calculated before initiating treatment with oral PUVAsol. These were compared with the respective scores after 12 weeks of regular treatment with PUVAsol. Statistical analysis was done using SPSS version 20.0. Results. Both PASI and DLQI showed statistically significant reduction after 12 weeks of regular treatment. 90% of patients responded favourably to PUVAsol therapy in the study and all the domains of DLQI showed significant reduction except domain of “work and school.” Conclusion. Our results show that regular PUVAsol treatment improves the physical appearance of disease as evident by decrease in PASI scores. It also improves the QoL of the patients. This study will add upon the growing evidence of efficacy of PUVAsol. |
| format | Article |
| id | doaj-art-3fc898483aff40d19237318da55e6f2c |
| institution | Kabale University |
| issn | 1687-6105 1687-6113 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Dermatology Research and Practice |
| spelling | doaj-art-3fc898483aff40d19237318da55e6f2c2025-02-03T06:11:25ZengWileyDermatology Research and Practice1687-61051687-61132014-01-01201410.1155/2014/291586291586Effect of Oral PUVAsol on the Quality of Life in Indian Patients Having Chronic Plaque PsoriasisPratik Gahalaut0Nitin Mishra1Puneet S. Soodan2Madhur K. Rastogi3Department of Dermatology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly 243202, IndiaDepartment of Dermatology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly 243202, IndiaDepartment of Dermatology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly 243202, IndiaDepartment of Dermatology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly 243202, IndiaBackground. Psoriasis is associated with a high impact on health-related QoL (quality of life). PUVAsol has been successfully used for treating psoriasis instead of standard PUVA therapy in developing countries. However, data for PUVAsol therapy and its effect on QoL in psoriatic patients is meagre. Objective. To investigate the effect of PUVAsol on the quality of life in patients having chronic plaque psoriasis. Materials and Methods. An observational prospective study done in patients having chronic plaque psoriasis. PASI and DLQI were calculated before initiating treatment with oral PUVAsol. These were compared with the respective scores after 12 weeks of regular treatment with PUVAsol. Statistical analysis was done using SPSS version 20.0. Results. Both PASI and DLQI showed statistically significant reduction after 12 weeks of regular treatment. 90% of patients responded favourably to PUVAsol therapy in the study and all the domains of DLQI showed significant reduction except domain of “work and school.” Conclusion. Our results show that regular PUVAsol treatment improves the physical appearance of disease as evident by decrease in PASI scores. It also improves the QoL of the patients. This study will add upon the growing evidence of efficacy of PUVAsol.http://dx.doi.org/10.1155/2014/291586 |
| spellingShingle | Pratik Gahalaut Nitin Mishra Puneet S. Soodan Madhur K. Rastogi Effect of Oral PUVAsol on the Quality of Life in Indian Patients Having Chronic Plaque Psoriasis Dermatology Research and Practice |
| title | Effect of Oral PUVAsol on the Quality of Life in Indian Patients Having Chronic Plaque Psoriasis |
| title_full | Effect of Oral PUVAsol on the Quality of Life in Indian Patients Having Chronic Plaque Psoriasis |
| title_fullStr | Effect of Oral PUVAsol on the Quality of Life in Indian Patients Having Chronic Plaque Psoriasis |
| title_full_unstemmed | Effect of Oral PUVAsol on the Quality of Life in Indian Patients Having Chronic Plaque Psoriasis |
| title_short | Effect of Oral PUVAsol on the Quality of Life in Indian Patients Having Chronic Plaque Psoriasis |
| title_sort | effect of oral puvasol on the quality of life in indian patients having chronic plaque psoriasis |
| url | http://dx.doi.org/10.1155/2014/291586 |
| work_keys_str_mv | AT pratikgahalaut effectoforalpuvasolonthequalityoflifeinindianpatientshavingchronicplaquepsoriasis AT nitinmishra effectoforalpuvasolonthequalityoflifeinindianpatientshavingchronicplaquepsoriasis AT puneetssoodan effectoforalpuvasolonthequalityoflifeinindianpatientshavingchronicplaquepsoriasis AT madhurkrastogi effectoforalpuvasolonthequalityoflifeinindianpatientshavingchronicplaquepsoriasis |