Dark Signals in the Choroidal Vasculature on Optical Coherence Tomography Angiography: An Artefact or Not?

Optical coherence tomography angiography (OCTA) based on mathematical processing of sequentially acquired structural OCT images has been applied widely in both retinal and choroidal research and may have advantages over traditional angiography. Images obtained by OCTA are rendered under the assumpti...

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Main Authors: Rui Hua, Hailin Wang
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2017/5498125
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author Rui Hua
Hailin Wang
author_facet Rui Hua
Hailin Wang
author_sort Rui Hua
collection DOAJ
description Optical coherence tomography angiography (OCTA) based on mathematical processing of sequentially acquired structural OCT images has been applied widely in both retinal and choroidal research and may have advantages over traditional angiography. Images obtained by OCTA are rendered under the assumption that the only moving entity in the retina is blood flow. Optical phenomena and image processing algorithms may create imaging artefacts. Therefore, OCTA images require careful interpretation. This review discusses the dark signals seen in the choroidal vasculature on OCTA using multiple factor analysis. For accurate and comprehensive interpretation of the choroidal vasculature, we recommend simultaneous consideration of the laser light penetration depth and masking effect of retinal pigment epithelium, the orientation of vessels in relation to the scanning lasers and blood flow, the range of regional detectable velocity of blood flow, atrophic tissues in the periphery, and absorption of superior vessels on the scanning laser.
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series Journal of Ophthalmology
spelling doaj-art-3fc491b1a0884e6c882b3622303346cd2025-02-03T01:28:50ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/54981255498125Dark Signals in the Choroidal Vasculature on Optical Coherence Tomography Angiography: An Artefact or Not?Rui Hua0Hailin Wang1Department of Ophthalmology, First Hospital of China Medical University, Shenyang, ChinaDepartment of Ophthalmology, The Fourth People’s Hospital of Shenyang, Shenyang, ChinaOptical coherence tomography angiography (OCTA) based on mathematical processing of sequentially acquired structural OCT images has been applied widely in both retinal and choroidal research and may have advantages over traditional angiography. Images obtained by OCTA are rendered under the assumption that the only moving entity in the retina is blood flow. Optical phenomena and image processing algorithms may create imaging artefacts. Therefore, OCTA images require careful interpretation. This review discusses the dark signals seen in the choroidal vasculature on OCTA using multiple factor analysis. For accurate and comprehensive interpretation of the choroidal vasculature, we recommend simultaneous consideration of the laser light penetration depth and masking effect of retinal pigment epithelium, the orientation of vessels in relation to the scanning lasers and blood flow, the range of regional detectable velocity of blood flow, atrophic tissues in the periphery, and absorption of superior vessels on the scanning laser.http://dx.doi.org/10.1155/2017/5498125
spellingShingle Rui Hua
Hailin Wang
Dark Signals in the Choroidal Vasculature on Optical Coherence Tomography Angiography: An Artefact or Not?
Journal of Ophthalmology
title Dark Signals in the Choroidal Vasculature on Optical Coherence Tomography Angiography: An Artefact or Not?
title_full Dark Signals in the Choroidal Vasculature on Optical Coherence Tomography Angiography: An Artefact or Not?
title_fullStr Dark Signals in the Choroidal Vasculature on Optical Coherence Tomography Angiography: An Artefact or Not?
title_full_unstemmed Dark Signals in the Choroidal Vasculature on Optical Coherence Tomography Angiography: An Artefact or Not?
title_short Dark Signals in the Choroidal Vasculature on Optical Coherence Tomography Angiography: An Artefact or Not?
title_sort dark signals in the choroidal vasculature on optical coherence tomography angiography an artefact or not
url http://dx.doi.org/10.1155/2017/5498125
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