Research status of the characteristics of anorectal microbiome associated with high-grade anal intraepithelial neoplasm
［Abstract］High-grade anal intraepithelial neoplasm represents a precancerous lesion of anal squamous cell carcinoma. Recent studies have demonstrated significant differences in the composition and characteristics of the anorectal microbiome between the general population and high-risk individuals/pa...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Colorectal & Anal Surgery
2024-12-01
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| Series: | 结直肠肛门外科 |
| Subjects: | |
| Online Access: | https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=482&cateName=2024%E5%B9%B4%20%E7%AC%AC30%E5%8D%B7%20%E7%AC%AC6%E6%9C%9F |
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| author | Chen Zeyang Fang Jingjing Pan Shaorong Li Yalun Liu Xiaoyu Tian Tian Zhang Jianhua Shao Wanjin |
| author_facet | Chen Zeyang Fang Jingjing Pan Shaorong Li Yalun Liu Xiaoyu Tian Tian Zhang Jianhua Shao Wanjin |
| author_sort | Chen Zeyang |
| collection | DOAJ |
| description | ［Abstract］High-grade anal intraepithelial neoplasm represents a precancerous lesion of anal squamous cell carcinoma. Recent studies have demonstrated significant differences in the composition and characteristics of the anorectal microbiome between the general population and high-risk individuals/patients with high-grade anal intraepithelial neoplasm and anal squamous cell carcinoma. This paper aims to review the characteristics of the anorectal microbiome in high-risk individuals/patients with high-grade anal intraepithelial neoplasm and anal squamous cell carcinoma, aiming to provide a theoretical foundation for elucidating the biological mechanisms underlying the progression of high-grade anal intraepithelial neoplasm and exploring novel diagnostic and therapeutic approaches for this condition. |
| format | Article |
| id | doaj-art-3fbfda4ce77d4e289632ce42cd2b0776 |
| institution | OA Journals |
| issn | 1674-0491 |
| language | zho |
| publishDate | 2024-12-01 |
| publisher | Editorial Office of Journal of Colorectal & Anal Surgery |
| record_format | Article |
| series | 结直肠肛门外科 |
| spelling | doaj-art-3fbfda4ce77d4e289632ce42cd2b07762025-08-20T01:50:59ZzhoEditorial Office of Journal of Colorectal & Anal Surgery结直肠肛门外科1674-04912024-12-0130668368710.19668/j.cnki.issn1674-0491.2024.06.006Research status of the characteristics of anorectal microbiome associated with high-grade anal intraepithelial neoplasmChen Zeyang0Fang Jingjing1Pan Shaorong2Li Yalun3Liu Xiaoyu4Tian Tian5Zhang Jianhua6Shao Wanjin7Department of Gastrointestinal Surgery, Peking University First Hospital, Beijing 100034, ChinaDepartment of Gastrointestinal Surgery, Peking University First Hospital, Beijing 100034, ChinaDepartment of Gastrointestinal Surgery, Peking University First Hospital, Beijing 100034, ChinaDepartment of Gastrointestinal Surgery, Peking University First Hospital, Beijing 100034, ChinaGeneral Surgical Outpatient Clinic, Peking University First Hospital, Beijing 100034, ChinaSchool of Public Health, Xinjiang Medical University, Urumqi 830000, Xinjiang, ChinaDepartment of Anorectal Surgery, Peking University First Hospital Taiyuan Hospital, Taiyuan 030024, Shanxi, ChinaDepartment of Anorectal Surgery, Shenzhen TCM Anorectal Hospital (Futian), Shenzhen 518031, Guangdong, China［Abstract］High-grade anal intraepithelial neoplasm represents a precancerous lesion of anal squamous cell carcinoma. Recent studies have demonstrated significant differences in the composition and characteristics of the anorectal microbiome between the general population and high-risk individuals/patients with high-grade anal intraepithelial neoplasm and anal squamous cell carcinoma. This paper aims to review the characteristics of the anorectal microbiome in high-risk individuals/patients with high-grade anal intraepithelial neoplasm and anal squamous cell carcinoma, aiming to provide a theoretical foundation for elucidating the biological mechanisms underlying the progression of high-grade anal intraepithelial neoplasm and exploring novel diagnostic and therapeutic approaches for this condition.https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=482&cateName=2024%E5%B9%B4%20%E7%AC%AC30%E5%8D%B7%20%E7%AC%AC6%E6%9C%9Fanal squamous cell carcinomahigh-grade anal intraepithelial neoplasmanorectal microbiomediagnostic biomarkers |
| spellingShingle | Chen Zeyang Fang Jingjing Pan Shaorong Li Yalun Liu Xiaoyu Tian Tian Zhang Jianhua Shao Wanjin Research status of the characteristics of anorectal microbiome associated with high-grade anal intraepithelial neoplasm 结直肠肛门外科 anal squamous cell carcinoma high-grade anal intraepithelial neoplasm anorectal microbiome diagnostic biomarkers |
| title | Research status of the characteristics of anorectal microbiome associated with high-grade anal intraepithelial neoplasm |
| title_full | Research status of the characteristics of anorectal microbiome associated with high-grade anal intraepithelial neoplasm |
| title_fullStr | Research status of the characteristics of anorectal microbiome associated with high-grade anal intraepithelial neoplasm |
| title_full_unstemmed | Research status of the characteristics of anorectal microbiome associated with high-grade anal intraepithelial neoplasm |
| title_short | Research status of the characteristics of anorectal microbiome associated with high-grade anal intraepithelial neoplasm |
| title_sort | research status of the characteristics of anorectal microbiome associated with high grade anal intraepithelial neoplasm |
| topic | anal squamous cell carcinoma high-grade anal intraepithelial neoplasm anorectal microbiome diagnostic biomarkers |
| url | https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=482&cateName=2024%E5%B9%B4%20%E7%AC%AC30%E5%8D%B7%20%E7%AC%AC6%E6%9C%9F |
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