MRI findings in organophosphate-induced delayed neuropathy: A case report

Organophosphate poisoning, including malathion ingestion, is a common method of suicide in some regions. This case involves a 24-year-old male who ingested malathion in a suicide attempt. Four weeks postingestion, the patient developed progressive neurological deterioration with motor deficits, seiz...

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Main Authors: Salma Moussaoui, Salma El Ouadih, Anas Orgi, Aicha Merzem, Hasna Belgadir, Omar Amriss, Nadia Moussali, Naima El Benna
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043324013062
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author Salma Moussaoui
Salma El Ouadih
Anas Orgi
Aicha Merzem
Hasna Belgadir
Omar Amriss
Nadia Moussali
Naima El Benna
author_facet Salma Moussaoui
Salma El Ouadih
Anas Orgi
Aicha Merzem
Hasna Belgadir
Omar Amriss
Nadia Moussali
Naima El Benna
author_sort Salma Moussaoui
collection DOAJ
description Organophosphate poisoning, including malathion ingestion, is a common method of suicide in some regions. This case involves a 24-year-old male who ingested malathion in a suicide attempt. Four weeks postingestion, the patient developed progressive neurological deterioration with motor deficits, seizures, and altered consciousness. MRI revealed diffuse hyperintensities in the corpus callosum, subcortical white matter, and other central nervous system structures, consistent with organophosphate-induced delayed neuropathy (OPIDN). Despite corticosteroid therapy, the patient's condition worsened due to septic shock, leading to death. This case highlights the importance of MRI in diagnosing OPIDN which remains rare and poorly documented in the literature. It also emphasizes the need for timely imaging to guide treatment and monitor disease progression.
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institution Kabale University
issn 1930-0433
language English
publishDate 2025-03-01
publisher Elsevier
record_format Article
series Radiology Case Reports
spelling doaj-art-3fb903d24f584e6cb3d39ea7bf1269cc2025-01-18T05:03:52ZengElsevierRadiology Case Reports1930-04332025-03-0120313451349MRI findings in organophosphate-induced delayed neuropathy: A case reportSalma Moussaoui0Salma El Ouadih1Anas Orgi2Aicha Merzem3Hasna Belgadir4Omar Amriss5Nadia Moussali6Naima El Benna7Corresponding author.; Radiology Department of 20 August 1953 Hospital, University Hospital Center Ibn Rochd, Casablanca 20100, MoroccoRadiology Department of 20 August 1953 Hospital, University Hospital Center Ibn Rochd, Casablanca 20100, MoroccoRadiology Department of 20 August 1953 Hospital, University Hospital Center Ibn Rochd, Casablanca 20100, MoroccoRadiology Department of 20 August 1953 Hospital, University Hospital Center Ibn Rochd, Casablanca 20100, MoroccoRadiology Department of 20 August 1953 Hospital, University Hospital Center Ibn Rochd, Casablanca 20100, MoroccoRadiology Department of 20 August 1953 Hospital, University Hospital Center Ibn Rochd, Casablanca 20100, MoroccoRadiology Department of 20 August 1953 Hospital, University Hospital Center Ibn Rochd, Casablanca 20100, MoroccoRadiology Department of 20 August 1953 Hospital, University Hospital Center Ibn Rochd, Casablanca 20100, MoroccoOrganophosphate poisoning, including malathion ingestion, is a common method of suicide in some regions. This case involves a 24-year-old male who ingested malathion in a suicide attempt. Four weeks postingestion, the patient developed progressive neurological deterioration with motor deficits, seizures, and altered consciousness. MRI revealed diffuse hyperintensities in the corpus callosum, subcortical white matter, and other central nervous system structures, consistent with organophosphate-induced delayed neuropathy (OPIDN). Despite corticosteroid therapy, the patient's condition worsened due to septic shock, leading to death. This case highlights the importance of MRI in diagnosing OPIDN which remains rare and poorly documented in the literature. It also emphasizes the need for timely imaging to guide treatment and monitor disease progression.http://www.sciencedirect.com/science/article/pii/S1930043324013062Organophosphate-Induced delayed neuropathyMRICase report
spellingShingle Salma Moussaoui
Salma El Ouadih
Anas Orgi
Aicha Merzem
Hasna Belgadir
Omar Amriss
Nadia Moussali
Naima El Benna
MRI findings in organophosphate-induced delayed neuropathy: A case report
Radiology Case Reports
Organophosphate-Induced delayed neuropathy
MRI
Case report
title MRI findings in organophosphate-induced delayed neuropathy: A case report
title_full MRI findings in organophosphate-induced delayed neuropathy: A case report
title_fullStr MRI findings in organophosphate-induced delayed neuropathy: A case report
title_full_unstemmed MRI findings in organophosphate-induced delayed neuropathy: A case report
title_short MRI findings in organophosphate-induced delayed neuropathy: A case report
title_sort mri findings in organophosphate induced delayed neuropathy a case report
topic Organophosphate-Induced delayed neuropathy
MRI
Case report
url http://www.sciencedirect.com/science/article/pii/S1930043324013062
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