Unraveling the Role of the Tumor Extracellular Matrix to Inform Nanoparticle Design for Nanomedicine

Unraveling the Role of the Tumor Extracellular Matrix to Inform Nanoparticle Design for Nanomedicine

Abstract The extracellular matrix (ECM)—and its mechanobiology—regulates key cellular functions that drive tumor growth and development. Accordingly, mechanotherapy is emerging as an effective approach to treat fibrotic diseases such as cancer. Through restoring the ECM to healthy‐like conditions, t...

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Bibliographic Details
Main Authors: Marco Cassani, Soraia Fernandes, Stefania Pagliari, Francesca Cavalieri, Frank Caruso, Giancarlo Forte
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
cancer therapy
ECM
mechanobiology
mechanotherapy
nanomedicine
Online Access:https://doi.org/10.1002/advs.202409898
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