Dynamic changes of intracellular signals in ATTR Tyr114Cys amyloidosis

Dynamic changes of intracellular signals in ATTR Tyr114Cys amyloidosis

Hereditary transthyretin (TTR) amyloidosis (ATTRv amyloidosis) is an autosomal dominant disease caused by various TTR mutations. Despite the fact that ATTR Tyr114Cys (p.Tyr134Cys) amyloidosis (tyrosine to cysteine at codon 114) exhibits poorer prognosis than other ATTRv amyloidosis and leads to deat...

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Bibliographic Details
Main Authors: Kenta Ouchi, Takeshi Masuda, Kou Yonemaru, Kaori Isono, Yuki Ohya, Nobuaki Shiraki, Masayoshi Tasaki, Yukihiro Inomata, Mitsuharu Ueda, Takumi Era, Shoen Kume, Yukio Ando, Hirofumi Jono
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Biochemistry and Biophysics Reports
Subjects:
ATTR amyloidosis
Transthyretin
Induced pluripotent stem cells
Proteomic analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580825000998
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