Perturbomics: CRISPR–Cas screening-based functional genomics approach for drug target discovery
Abstract Despite more than two decades since the completion of the first draft of the Human Genome Project, a substantial proportion of human genes remain poorly characterized in terms of their functions. Functional genomics aims to elucidate the roles and interactions of genes and genetic elements,...
Saved in:
| Main Authors: | Byung-Sun Park, Mieun Lee, Jaeyeol Kim, Tackhoon Kim |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
|
| Series: | Experimental and Molecular Medicine |
| Online Access: | https://doi.org/10.1038/s12276-025-01487-0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer
by: Tackhoon Kim, et al.
Published: (2025-04-01) -
Engineered CRISPR-Cas9 for Streptomyces sp. genome editing to improve specialized metabolite production
by: Duck Gyun Kim, et al.
Published: (2025-01-01) -
The application of CRISPR/Cas9–based genome-wide screening to disease research
by: Xiuqin Chen, et al.
Published: (2025-02-01) -
Therapeutic Targeting in Ovarian Cancer: Nano-Enhanced CRISPR/Cas9 Gene Editing and Drug Combination Therapy
by: Kim HK, et al.
Published: (2025-03-01) -
CRISPR/Cas-based customization of pooled CRISPR libraries.
by: Jiyeon Kweon, et al.
Published: (2018-01-01)