Temporal dynamics of lymphocytes in prostate cancer patients treated with proton therapy

Temporal dynamics of lymphocytes in prostate cancer patients treated with proton therapy

Radiotherapy can be both immunosuppressive and immunostimulatory. Radiation-induced lymphopenia (RIL) is an ongoing challenge in cancer treatment. We investigated weekly changes in the absolute lymphocyte count (ALC) during proton radiotherapy, evaluating the effects of different dosage, fractionati...

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Bibliographic Details
Main Authors: Sarah Salih Al-Hamami, Samuel Kurucz, Vladimír Vondráček, Vladimír Pekar, Michal Andrlík, Kateřina Dědečková, Iva Benešová, Alexandra Haas, Barbora Ondrová, Andrea Pasztorová, Pavel Vítek, Jiří Kubeš
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
proton therapy
radiation oncology
hypofractionation
immunostimulation
lymphopenia
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1470876/full
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