Tuberculous Panophthalmitis with Lymphadenitis and Central Nervous System Tuberculoma
Tuberculosis (TB) is a serious infectious disease that spreads globally. The ocular manifestations of TB are uncommon and diverse. TB panophthalmitis has been rarely reported. Here, we described a 38-year-old Thai man presenting with panophthalmitis of the right eye. Further investigation showed tha...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2016/6785382 |
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| author | Sirawat Srichatrapimuk Duangkamon Wattanatranon Somnuek Sungkanuparph |
| author_facet | Sirawat Srichatrapimuk Duangkamon Wattanatranon Somnuek Sungkanuparph |
| author_sort | Sirawat Srichatrapimuk |
| collection | DOAJ |
| description | Tuberculosis (TB) is a serious infectious disease that spreads globally. The ocular manifestations of TB are uncommon and diverse. TB panophthalmitis has been rarely reported. Here, we described a 38-year-old Thai man presenting with panophthalmitis of the right eye. Further investigation showed that he had concurrent TB lymphadenitis and central nervous system (CNS) tuberculoma, as well as HIV infection, with a CD4 cell count of 153 cells/mm3. Despite the initial response to antituberculous agents, the disease had subsequently progressed and enucleation was required. The pathological examination revealed acute suppurative granulomatous panophthalmitis with retinal detachment. Further staining demonstrated acid-fast bacilli in the tissue. Colonies of Mycobacterium tuberculosis were obtained from tissue culture. He was treated with antiretroviral agents for HIV infection and 12 months of antituberculous agents. Clinicians should be aware of the possibility of TB in the differential diagnosis of endophthalmitis and panophthalmitis, especially in regions where TB is endemic. |
| format | Article |
| id | doaj-art-3f67c5674485480cb68dd8438ed5e2e7 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-3f67c5674485480cb68dd8438ed5e2e72025-02-03T01:09:25ZengWileyCase Reports in Infectious Diseases2090-66252090-66332016-01-01201610.1155/2016/67853826785382Tuberculous Panophthalmitis with Lymphadenitis and Central Nervous System TuberculomaSirawat Srichatrapimuk0Duangkamon Wattanatranon1Somnuek Sungkanuparph2Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, ThailandDepartment of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, ThailandDepartment of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, ThailandTuberculosis (TB) is a serious infectious disease that spreads globally. The ocular manifestations of TB are uncommon and diverse. TB panophthalmitis has been rarely reported. Here, we described a 38-year-old Thai man presenting with panophthalmitis of the right eye. Further investigation showed that he had concurrent TB lymphadenitis and central nervous system (CNS) tuberculoma, as well as HIV infection, with a CD4 cell count of 153 cells/mm3. Despite the initial response to antituberculous agents, the disease had subsequently progressed and enucleation was required. The pathological examination revealed acute suppurative granulomatous panophthalmitis with retinal detachment. Further staining demonstrated acid-fast bacilli in the tissue. Colonies of Mycobacterium tuberculosis were obtained from tissue culture. He was treated with antiretroviral agents for HIV infection and 12 months of antituberculous agents. Clinicians should be aware of the possibility of TB in the differential diagnosis of endophthalmitis and panophthalmitis, especially in regions where TB is endemic.http://dx.doi.org/10.1155/2016/6785382 |
| spellingShingle | Sirawat Srichatrapimuk Duangkamon Wattanatranon Somnuek Sungkanuparph Tuberculous Panophthalmitis with Lymphadenitis and Central Nervous System Tuberculoma Case Reports in Infectious Diseases |
| title | Tuberculous Panophthalmitis with Lymphadenitis and Central Nervous System Tuberculoma |
| title_full | Tuberculous Panophthalmitis with Lymphadenitis and Central Nervous System Tuberculoma |
| title_fullStr | Tuberculous Panophthalmitis with Lymphadenitis and Central Nervous System Tuberculoma |
| title_full_unstemmed | Tuberculous Panophthalmitis with Lymphadenitis and Central Nervous System Tuberculoma |
| title_short | Tuberculous Panophthalmitis with Lymphadenitis and Central Nervous System Tuberculoma |
| title_sort | tuberculous panophthalmitis with lymphadenitis and central nervous system tuberculoma |
| url | http://dx.doi.org/10.1155/2016/6785382 |
| work_keys_str_mv | AT sirawatsrichatrapimuk tuberculouspanophthalmitiswithlymphadenitisandcentralnervoussystemtuberculoma AT duangkamonwattanatranon tuberculouspanophthalmitiswithlymphadenitisandcentralnervoussystemtuberculoma AT somnueksungkanuparph tuberculouspanophthalmitiswithlymphadenitisandcentralnervoussystemtuberculoma |