The role of sleep in Alzheimer’s disease: a mini review
Sleep is a stereotyped and well-preserved series of neurophysiological states that are essential for overall health and brain functioning. Emerging research suggests that sleep disturbances are not only associated with but also causally contribute to neurodegenerative disease onset and progression....
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2025-02-01
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Series: | Frontiers in Neuroscience |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2025.1428733/full |
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author | Jay Pathmanathan M. Brandon Westover Sudhir Sivakumaran Jacob Donoghue Corey B. Puryear |
author_facet | Jay Pathmanathan M. Brandon Westover Sudhir Sivakumaran Jacob Donoghue Corey B. Puryear |
author_sort | Jay Pathmanathan |
collection | DOAJ |
description | Sleep is a stereotyped and well-preserved series of neurophysiological states that are essential for overall health and brain functioning. Emerging research suggests that sleep disturbances are not only associated with but also causally contribute to neurodegenerative disease onset and progression. This mini-review examines some of the current knowledge and evidence for relationships between sleep abnormalities and Alzheimer’s disease within context of possible uses and limitations of sleep biomarkers for evaluation of Alzheimer’s disease. Understanding these relationships could lead to readily accessible and easily quantifiable biomarkers of Alzheimer’s dementia. |
format | Article |
id | doaj-art-3f4093b169dc4087931faf26c0b95bc3 |
institution | Kabale University |
issn | 1662-453X |
language | English |
publishDate | 2025-02-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Neuroscience |
spelling | doaj-art-3f4093b169dc4087931faf26c0b95bc32025-02-05T07:32:33ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2025-02-011910.3389/fnins.2025.14287331428733The role of sleep in Alzheimer’s disease: a mini reviewJay PathmanathanM. Brandon WestoverSudhir SivakumaranJacob DonoghueCorey B. PuryearSleep is a stereotyped and well-preserved series of neurophysiological states that are essential for overall health and brain functioning. Emerging research suggests that sleep disturbances are not only associated with but also causally contribute to neurodegenerative disease onset and progression. This mini-review examines some of the current knowledge and evidence for relationships between sleep abnormalities and Alzheimer’s disease within context of possible uses and limitations of sleep biomarkers for evaluation of Alzheimer’s disease. Understanding these relationships could lead to readily accessible and easily quantifiable biomarkers of Alzheimer’s dementia.https://www.frontiersin.org/articles/10.3389/fnins.2025.1428733/fullsleepAlzheimer’s diseasereviewsleep monitoringneurodegenerative disease |
spellingShingle | Jay Pathmanathan M. Brandon Westover Sudhir Sivakumaran Jacob Donoghue Corey B. Puryear The role of sleep in Alzheimer’s disease: a mini review Frontiers in Neuroscience sleep Alzheimer’s disease review sleep monitoring neurodegenerative disease |
title | The role of sleep in Alzheimer’s disease: a mini review |
title_full | The role of sleep in Alzheimer’s disease: a mini review |
title_fullStr | The role of sleep in Alzheimer’s disease: a mini review |
title_full_unstemmed | The role of sleep in Alzheimer’s disease: a mini review |
title_short | The role of sleep in Alzheimer’s disease: a mini review |
title_sort | role of sleep in alzheimer s disease a mini review |
topic | sleep Alzheimer’s disease review sleep monitoring neurodegenerative disease |
url | https://www.frontiersin.org/articles/10.3389/fnins.2025.1428733/full |
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