Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1α Protein Replacement Human Cell Lines.

Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1α Protein Replacement Human Cell Lines.

The snoMEN (snoRNA Modulator of gene ExpressioN) vector technology was developed from a human box C/D snoRNA, HBII-180C, which contains an internal sequence that can be manipulated to make it complementary to RNA targets, allowing knock-down of targeted genes. Here we have screened additional human...

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Bibliographic Details
Main Authors: Motoharu Ono, Kayo Yamada, Dalila Bensaddek, Vackar Afzal, John Biddlestone, Brian Ortmann, Sharon Mudie, Vincent Boivin, Michelle S Scott, Sonia Rocha, Angus I Lamond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0154759&type=printable
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